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Optimizing Resuscitation After Cardiac Arrest in the Community

NCT ID: NCT00998140

Last Updated: 2020-11-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

1600 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-03-31

Study Completion Date

2021-10-31

Brief Summary

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Resuscitative efforts have been shown to be unsuccessful in most cases of out-of-hospital cardiac arrest (OHCA), and survivors who do recover cardiac function often sustain severe hypoxic brain damage. Time to efficacious care is a primary determinant of disability-free survival. In the Jerusalem district, only 9% of OHCA patients present with ventricular tachycardia/ventricular fibrillation (VT/VF) as the primary rhythm, whereas 77% present with asystole; this seems primarily to be the result of long collapse-to-arrival times. Nevertheless, overly zealous resuscitation is undertaken in a high proportion of arrests with a futile prognosis, leading to excessive costs.

Study hypotheses:

1. Subpopulations for whom intervention is futile/counter-productive are identifiable
2. Substantial waste of resources can be avoided
3. Optimization of emergency medical services (EMS) reorganization without adding resources is an achievable goal

Detailed Description

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Conditions

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Cardiopulmonary Arrest Outcome

Keywords

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resuscitation sudden death cardiopulmonary resuscitation emergency medical services termination of resuscitation ventricular fibrillation out-of-hospital cardiac arrest asystole medical futility withdrawing treatment transportation of patients health expenditures healthcare costs

Study Design

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Observational Model Type

COHORT

Study Time Perspective

OTHER

Eligibility Criteria

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Inclusion Criteria

* All victims of non-traumatic out-of hospital cardiopulmonary arrest (defined as the absence of either spontaneous respiration or palpable pulse or both) within the Jerusalem district.

Exclusion Criteria

* Patients with do-not-resuscitate orders or an advance directive to that effect.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Shaare Zedek Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Dr Sharon Einav

Dr.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Sharon Einav, MD

Role: PRINCIPAL_INVESTIGATOR

Shaare Zedek Medical Center

Locations

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Shaare Zedek Medical Center

Jerusalem, , Israel

Site Status

Countries

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Israel

References

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Pachys G, Kaufman N, Bdolah-Abram T, Kark JD, Einav S. Predictors of long-term survival after out-of-hospital cardiac arrest: the impact of Activities of Daily Living and Cerebral Performance Category scores. Resuscitation. 2014 Aug;85(8):1052-8. doi: 10.1016/j.resuscitation.2014.03.312. Epub 2014 Apr 12.

Reference Type RESULT
PMID: 24727137 (View on PubMed)

Other Identifiers

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NIHPR 08/90/a

Identifier Type: -

Identifier Source: org_study_id