Diamel in the Treatment of Type 2 Diabetic Patients Receiving Insulin Therapy

NCT ID: NCT00994266

Last Updated: 2011-04-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

116 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-10-31

Study Completion Date

2011-04-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study is to assess the efficacy of Diamel (dietary supplement) administration in the treatment of patients with type 2 diabetes receiving insulin therapy. The duration of this double-blind placebo controlled phase 3 clinical trial will be 24 weeks. The estimated number of patients to be recruited and randomized for the study is 116. Daily insulin requirements, blood glucose (fasting and post-prandial) concentrations, glycosylated hemoglobin (HbA1c), triglycerides and cholesterol will be assessed at the beginning and after 24 weeks of treatment.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Type 2 Diabetes

Keywords

Explore important study keywords that can help with search, categorization, and topic discovery.

Type 2 diabetes Diamel Dietary supplement

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Caregivers Investigators

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

A

Diamel

Group Type EXPERIMENTAL

Diamel

Intervention Type DIETARY_SUPPLEMENT

Two Diamel tablets (Orally administered) three times a day (just before each meal: breakfast, lunch and dinner), for 24 weeks, in combination with the standard treatment consisting in two daily doses of insulin and proper diet.

B

Placebo

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DIETARY_SUPPLEMENT

Two Placebo tablets (Orally administered) three times a day (just before each meal: breakfast, lunch and dinner), for 24 weeks, in combination with the standard treatment consisting in two daily doses of insulin and proper diet.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Diamel

Two Diamel tablets (Orally administered) three times a day (just before each meal: breakfast, lunch and dinner), for 24 weeks, in combination with the standard treatment consisting in two daily doses of insulin and proper diet.

Intervention Type DIETARY_SUPPLEMENT

Placebo

Two Placebo tablets (Orally administered) three times a day (just before each meal: breakfast, lunch and dinner), for 24 weeks, in combination with the standard treatment consisting in two daily doses of insulin and proper diet.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Type 2 diabetes with insulin therapy regimen of two daily doses.
* Signed informed consent.

Exclusion Criteria

* Type 1 diabetes.
* Type 2 diabetes with glibenclamide treatment.
* Nephropathy or liver condition diagnosed by clinical and/or biochemical examination.
* Sepsis.
* Pregnancy.
* HbA1c values greater than 10%.
Minimum Eligible Age

40 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Catalysis SL

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

"Abel Santamaría Cuadrado"General Hospital

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Maria Elena de la Uz Herrera, MSC

Role: PRINCIPAL_INVESTIGATOR

"Abel Santamaría Cuadrado" General Hospital

Arturo Hernández Yero, PhD

Role: STUDY_DIRECTOR

National Institute of Endocrinology

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Diabetes Care Center. "Abel Santamaría Cuadrado" General Hospital

Pinar del Río, Provincia de Pinar del Río, Cuba

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Cuba

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

CAT-0912-CU

Identifier Type: -

Identifier Source: org_study_id