Trial Outcomes & Findings for Cerebrospinal Fluid (CSF) Pharmacokinetics of Antimicrobials in Children (NCT NCT00991185)

NCT ID: NCT00991185

Last Updated: 2024-04-15

Results Overview

CSF:serum ration of vancomycin

Recruitment status

COMPLETED

Target enrollment

8 participants

Primary outcome timeframe

within 1 week of drug administration

Results posted on

2024-04-15

Participant Flow

Participant milestones

Participant milestones
Measure
Vancomycin
children that received vancomycin per standard of care
Overall Study
STARTED
8
Overall Study
COMPLETED
8
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Cerebrospinal Fluid (CSF) Pharmacokinetics of Antimicrobials in Children

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Vancomycin
n=8 Participants
children that received vancomycin per standard of care
Age, Continuous
4 years
n=5 Participants
Sex: Female, Male
Female
4 Participants
n=5 Participants
Sex: Female, Male
Male
4 Participants
n=5 Participants
Region of Enrollment
United States
8 participants
n=5 Participants

PRIMARY outcome

Timeframe: within 1 week of drug administration

CSF:serum ration of vancomycin

Outcome measures

Outcome measures
Measure
Vancomycin
n=8 Participants
children that received vancomycin per standard of care
CSF:Serum Ratio of Vancomycin
0.08 ratio
Interval 0.0 to 0.66

Adverse Events

Vancomycin

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

brian smith

duke

Phone: 919668951

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place