Comprehensive Cohort Study of Bracing for Adolescent Idiopathic Scoliosis (AIS): A Feasibility Study

NCT ID: NCT00989495

Last Updated: 2014-12-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

68 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-10-31

Study Completion Date

2011-11-30

Brief Summary

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The purpose of this study is to gain initial experience and information for proper planning and conduct of a confirmatory study (a multi-centre single-blind comprehensive cohort study of bracing).

Detailed Description

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The study has been completed.

Conditions

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Adolescent Idiopathic Scoliosis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Brace - Randomized

Participants were randomized to be braced

Group Type EXPERIMENTAL

Brace

Intervention Type DEVICE

Wearing a Thoraco-Lumbo-Sacral-Orthosis (TLSO) for a minimum of 20 hours per day

Observation - Randomized

Participants were randomized to be observed only

Group Type NO_INTERVENTION

No interventions assigned to this group

Brace - preference based

Participants chose to be braced

Group Type EXPERIMENTAL

Brace

Intervention Type DEVICE

Wearing a Thoraco-Lumbo-Sacral-Orthosis (TLSO) for a minimum of 20 hours per day

Observation - preference-based

Participants chose to be observed only

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Brace

Wearing a Thoraco-Lumbo-Sacral-Orthosis (TLSO) for a minimum of 20 hours per day

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. Diagnosis of AIS
2. Age ≥10 years
3. Risser sign 0-2
4. Cobb's angle 20 deg to \<25 deg with documented deterioration of at least 5 deg within the past 4 months (with a maximum of 10 days deviation), or 25 deg to \<30 deg

Exclusion Criteria

1. History of treatment of AIS
2. \>= 1 year postmenarchal (for girls only)
3. Physical or mental disability to adhere to bracing
4. Diagnosis of musculoskeletal or development illness that might be responsible for the spinal curvature
5. Structural thoracic scoliosis with apex above T7 (Note these patients are not suitable for under-arm brace)
6. Difficulty to read, understand, and complete the study questionnaires
7. Any criteria, which, in the opinion of the investigator, suggests that the subject would not be compliant with the study protocol
Minimum Eligible Age

10 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Scoliosis Research Society

OTHER

Sponsor Role collaborator

The University of Hong Kong

OTHER

Sponsor Role lead

Responsible Party

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Dr Daniel Yee Tak FONG

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Daniel YT Fong, PhD

Role: PRINCIPAL_INVESTIGATOR

The University of Hong Kong

Locations

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The Duchess of Kent Children's Hospital

Hong Kong, , China

Site Status

Countries

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China

Other Identifiers

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HKCTR-819

Identifier Type: REGISTRY

Identifier Source: secondary_id

dytfong

Identifier Type: -

Identifier Source: org_study_id