The Impact of GlowCaps Connect™ and Its Services on Hypertension Medication Adherence

NCT ID: NCT00985452

Last Updated: 2012-10-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

139 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-08-31

Study Completion Date

2010-08-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The investigators hypothesize that providing subjects on a once-a-day hypertension medication with GlowCaps ConnectTM will lead to an improvement in their medication adherence. The investigators propose to conduct a 6-month randomized control trial to assess the effect of the GlowCaps Connect™ system on the enhancement of hypertension medication adherence among subjects with a diagnosis of hypertension recruited from the greater Boston area. 130 subjects will be enrolled. Subjects will be randomized into either the control group or into one of two intervention groups.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Participants will use the GlowCap system for 6 months.

Group 1

* The GlowCap bottle provided for subjects in this group will passively track medication adherence over the course of the study
* The pill cap will collect data, but will not provide any visual or auditory alerts
* An Ethernet Gateway connector will collect adherence data from the pill bottle cap via a local wireless network. This data will be sent out of subject's home through the internet.

Group 2

* Subjects in this group will be given daily visual, auditory, and phone call reminders to take their medication via the GlowCap system if they fail to take their hypertension medication at the scheduled dose time
* An Ethernet Gateway connector will collect adherence data from the pill bottle cap via a local wireless network. This data will be sent out of subject's home through the internet.
* Subjects will receive Weekly and Monthly Progress Reports by email and mail, respectively. Reports will include information about medication adherence and target goals. If a subject does not opt-out, Monthly Progress Reports will also be sent to the subject's primary care physician (PCP)
* If the subject chooses, a friend or family member will receive a Weekly Progress Report by email
* If the subject chooses, he/she will receive prompts (via automated telephone call twice a month) to refill his/her prescription
* Subjects demonstrating consistent low adherence to medication will receive additional support in the form of calls from Vitality reminding them to take the medication.

Group 3

* Subjects in this group will be given daily visual, auditory, and phone call reminders to take their medication via the GlowCap system if they fail to take their hypertension medication at the scheduled dose time
* An Ethernet Gateway connector will collect adherence data from the pill bottle cap via a local wireless network. This data will be sent out of subject's home through the internet.
* Subjects will receive Weekly and Monthly Progress Reports by email and mail, respectively. Reports will include information about medication adherence and target goals. If a subject does not opt-out, Monthly Progress Reports will also be sent to the subject's primary care physician (PCP)
* If the subject chooses, a friend or family member will receive a Weekly Progress Report by email
* Subjects will receive financial incentives in the form of a check for meeting a target adherence goal of 80% adherence over each month. The check will be mailed to them at the end of the study.
* If the subjects chooses, he/she will receive prompts (via automated telephone call twice a month) to refill his/her prescription
* Subjects demonstrating consistent low adherence to medication will receive additional support in the form of calls from Vitality reminding them to take the medication and may receive increased financial incentives to meet their target.

Study subjects will attend two study visits, one at the beginning and one at the end of the 6 month period. At these visits they will have their blood pressure recorded and will be asked to complete a survey.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Medication Adherence

Keywords

Explore important study keywords that can help with search, categorization, and topic discovery.

Medication Adherence Hypertension

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

FACTORIAL

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Group 2: Intervention

Subjects in Group two will received an activated GlowCaps system, which will remind them to take their medication.

Group Type OTHER

GlowCaps Connect system

Intervention Type OTHER

The GlowCaps Connect system is an electronic medication reminder system, which provides reminders to help people to remember to take their medication.

Group 3: Intervention/financial incentive

Subjects in group 3 will receive an activated GlowCaps system, which will provide them with reminders to take their medication, Subjects in group 3 will also receive an additional financial incentive, the amount will be based on how often they remembered to take their medication during the 6-month study.

Group Type OTHER

GlowCaps Connect system

Intervention Type OTHER

The GlowCaps Connect system is an electronic medication reminder system, which provides reminders to help people to remember to take their medication.

Group 1: Control

Subjects in group one will receive a de-activated GlowCaps system, which will not provide the reminder service.

Group Type OTHER

Glow cap system - deactivated

Intervention Type OTHER

The Glow cap system - deactivated is an electronic medication system, which will track medication adherence.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

GlowCaps Connect system

The GlowCaps Connect system is an electronic medication reminder system, which provides reminders to help people to remember to take their medication.

Intervention Type OTHER

Glow cap system - deactivated

The Glow cap system - deactivated is an electronic medication system, which will track medication adherence.

Intervention Type OTHER

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

Vitality GlowCaps Connect Vitality GlowCaps

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Adult men and women age 18 and over
* Diagnosis of hypertension
* Take a once a day medication for hypertension
* Internet access via broadband (not dial-up)
* Home router
* A private email account
* Fluency in English (spoken and written)
* Have a Primary Care Physician

Exclusion Criteria

* People will be excluded if they are not able to adequately respond to researcher's questions or complete the surveys.
* People with significant cognitive deficits will be excluded.
* People will be excluded if they take more than three medications a day for hypertension.
* People will be excluded if they take more than five medications in one day.
* People will be excluded if they have total color blindness.
* People will be excluded if they are both blind and deaf.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Massachusetts General Hospital

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Joseph C. Kvedar

Director, Center for Connected Health

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Joseph C Kvedar, MD

Role: PRINCIPAL_INVESTIGATOR

Massachusetts General Hospital

Countries

Review the countries where the study has at least one active or historical site.

United States

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

2009-P-000254/3;MGH

Identifier Type: -

Identifier Source: org_study_id