Trial Outcomes & Findings for DHEA in Treating Women Undergoing Surgery for Stage I, Stage II, or Stage III Breast Cancer (NCT NCT00972023)

NCT ID: NCT00972023

Last Updated: 2019-09-17

Results Overview

Recruitment status

TERMINATED

Study phase

PHASE1

Target enrollment

1 participants

Primary outcome timeframe

Baseline, prior to DHEA treatment, within 48 hours prior to surgery and after 14 days of DHEA treatment.

Results posted on

2019-09-17

Participant Flow

Cancer center clinic

Participant milestones

Participant milestones
Measure
DHEA, Surgical Resection
DHEA, surgical resection: Day-14 (approx. 2 wks prior to surgery): begin a 2 week course of DHEA; Day-7 (approx. 1 wk after starting treatment): answer question about pill diary; Day 0 (approx. 2 wks after starting treatment, within 48 hours prior to surgery; DHEA: Administration will begin approxiately 14 days prior to surgery. Surgical resection: Surgical procedure of the invasive breast cancer
Overall Study
STARTED
1
Overall Study
COMPLETED
0
Overall Study
NOT COMPLETED
1

Reasons for withdrawal

Reasons for withdrawal
Measure
DHEA, Surgical Resection
DHEA, surgical resection: Day-14 (approx. 2 wks prior to surgery): begin a 2 week course of DHEA; Day-7 (approx. 1 wk after starting treatment): answer question about pill diary; Day 0 (approx. 2 wks after starting treatment, within 48 hours prior to surgery; DHEA: Administration will begin approxiately 14 days prior to surgery. Surgical resection: Surgical procedure of the invasive breast cancer
Overall Study
Withdrawal by Subject
1

Baseline Characteristics

DHEA in Treating Women Undergoing Surgery for Stage I, Stage II, or Stage III Breast Cancer

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
DHEA, Surgical Resection
n=1 Participants
Day-14 (approx. 2 wks prior to surgery): begin a 2 week course of DHEA; Day-7 (approx. 1 wk after starting treatment): answer question about pill diary; Day 0 (approx. 2 wks after starting treatment, within 48 hours prior to surgery; DHEA : DHEA administration will begin approxiately 14 days prior to surgery. Surgical resection : Surgical procedure of the invasive breast cancer
Age, Continuous
52 years
STANDARD_DEVIATION 0 • n=5 Participants
Sex: Female, Male
Female
1 Participants
n=5 Participants
Sex: Female, Male
Male
0 Participants
n=5 Participants
Region of Enrollment
United States
1 participants
n=5 Participants

PRIMARY outcome

Timeframe: Baseline, prior to DHEA treatment, within 48 hours prior to surgery and after 14 days of DHEA treatment.

Population: Per protocol, although no analysis was completed, patient chose to receive neoadjuvant chemo instead of surgery \& refused follow up.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Baseline, prior to DHEA treatment, within 48 hours prior to surgery and after 14 days of DHEA treatment.

Population: Per protocol, although no analysis was completed, patient chose to receive neoadjuvant chemo instead of surgery \& refused follow up.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Baseline, prior to DHEA treatment, within 48 hours prior to surgery and after 14 days of DHEA treatment.

Population: Per protocol, although no analysis was completed, patient chose to receive neoadjuvant chemo instead of surgery \& refused follow up.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Within 48 hours prior to surgery and after 14 days of DHEA treatment.

Population: Per protocol, although no analysis was completed, patient chose to receive neoadjuvant chemo instead of surgery \& refused follow up.

Outcome measures

Outcome data not reported

Adverse Events

DHEA, Surgical Resection

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Elaina Gartner

Barbara Ann Karmanos Cancer Institute

Phone: 800-527-6266

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place