Stereotactic Hypofractionated Radiosurgery for Early Stage Prostate Cancer

NCT ID: NCT00969202

Last Updated: 2015-11-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE1

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-08-31

Study Completion Date

2016-12-31

Brief Summary

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The purpose of this trial is to evaluate a short course of very focused (stereotactic) external beam radiation therapy for the treatment of early stage prostate cancer.

The investigators will gather scientific information about the tolerance and side effects this type of radiation. The investigators will then compare these results with those of standard 8 week course of external beam radiation therapy to see if this study treatment is equally or more effective in treating prostate cancer.

Detailed Description

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Conditions

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Prostate Cancer

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Stereotactic Radiosurgery using NovalisTx

Single arm study using the Novalis Tx to perform radiosurgery to treat low grade prostate cancer.

Group Type EXPERIMENTAL

Stereotactic Radiosurgery using the Novalis Tx

Intervention Type RADIATION

Five treatments given every other day.

Interventions

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Stereotactic Radiosurgery using the Novalis Tx

Five treatments given every other day.

Intervention Type RADIATION

Other Intervention Names

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Novalis Tx Novalis

Eligibility Criteria

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Inclusion Criteria

* Histologically confirmed adenocarcinoma of the prostate
* Gleason score ≤ 6 and low volume Gleason 7 (3+4)
* PSA \< 10
* Clinical Stage of T2a or less
* Ability to understand and the willingness to sign a written informed consent document

Exclusion Criteria

* Prior radiation treatment for prostate cancer
* Gleason score \> 7
* PSA \> 10
* Clinical Stage of T2b or greater
Minimum Eligible Age

18 Years

Maximum Eligible Age

99 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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San Diego Radiosurgery

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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P. Brian Volpp, MD, MPH

Role: PRINCIPAL_INVESTIGATOR

San Diego Radiosurgery/X-Ray Medical Group-Radiation Oncology

Locations

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San Diego Radiosurgery at Palomar Medical Center

Escondido, California, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Jennifer Joiner

Role: CONTACT

760-739-3185

Jeremy Legg

Role: CONTACT

615-920-1282

Facility Contacts

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Jennifer Joiner

Role: primary

760-739-3185

Other Identifiers

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SDRS0001

Identifier Type: -

Identifier Source: org_study_id