A Study to Evaluate Food Effect on ONO-5920/YM529 Intermittent Formulation

NCT ID: NCT00965978

Last Updated: 2009-10-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1

Total Enrollment

48 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-07-31

Study Completion Date

2009-09-30

Brief Summary

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The aim of the study is to evaluate the effects of food intake on the plasma concentration profile of YNO-5920/YM529 in post menopausal women.

Detailed Description

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Conditions

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Osteoporosis Osteoporosis, Postmenopausal Bone Diseases

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Low dose group

Receives low dose of ONO-5920/YM529 with and without food

Group Type EXPERIMENTAL

ONO-5920 / YM529

Intervention Type DRUG

oral

High dose group

Receives high dose of ONO-5920/YM529 with and without food

Group Type EXPERIMENTAL

ONO-5920 / YM529

Intervention Type DRUG

oral

Interventions

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ONO-5920 / YM529

oral

Intervention Type DRUG

Other Intervention Names

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Minodronic Acid

Eligibility Criteria

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Inclusion Criteria

* Post menopausal women (at least 2 years after menopause)
* Body weight: more than 40.0 Kg and less than 70.0 Kg
* BMI: more than 17.6 and less than 30.0

Exclusion Criteria

* Receives investigational drug within 120 day before the study
* Blood donation before the study
* With abnormal laboratory values
Minimum Eligible Age

45 Years

Maximum Eligible Age

81 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Ono Pharma USA Inc

INDUSTRY

Sponsor Role collaborator

Astellas Pharma Inc

INDUSTRY

Sponsor Role lead

Responsible Party

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Astellas Pharma, Inc

Principal Investigators

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Use Central Contact

Role: STUDY_CHAIR

Astellas Pharma Inc

Locations

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Kantou, , Japan

Site Status

Countries

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Japan

Other Identifiers

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529-CL-027

Identifier Type: -

Identifier Source: org_study_id

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