Motor Development and Orthoses in Spinal Muscular Atrophy (SMA)

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

80 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-10-12

Study Completion Date

2011-04-04

Brief Summary

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Spinal Muscular Atrophy (SMA) is neurodegenerative disease of anterior horn cells of spinal cord and represents the second more frequent pathology in childhood.

According to the age of onset and the maximum motor function the disorder is classified in 4 types. Patients with SMA II and SMA III often use orthoses to achieve postural and dynamic functions.

In this retrospective observational study the investigators describe the characteristics of sitting position, standing and walking correlated to type and time of orthoses used.

Detailed Description

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We collect data from patients with SMA II and SMA III referred to UDGEE from jan. 1995 to dec. 2008.

We estimate to achieve informations about 50-70 patients.

Conditions

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Spinal Muscular Atrophy

Keywords

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spinal muscular atrophy motor development orthoses

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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SMA II and SMA III

patients with SMA II and SMA III

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Clinical and genetics diagnosis of SMA II and SMA III

Exclusion Criteria

* N/A

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Adriano Ferrari, MD

Role: STUDY_DIRECTOR

Hospital S.Maria Nuova Reggio Emilia Italy

Locations

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UDGEE Hospital S.Maria Nuova

Reggio Emilia, RE, Italy

Site Status

Countries

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Italy

References

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Wang CH, Finkel RS, Bertini ES, Schroth M, Simonds A, Wong B, Aloysius A, Morrison L, Main M, Crawford TO, Trela A; Participants of the International Conference on SMA Standard of Care. Consensus statement for standard of care in spinal muscular atrophy. J Child Neurol. 2007 Aug;22(8):1027-49. doi: 10.1177/0883073807305788.

Reference Type BACKGROUND

PMID: 17761659 (View on PubMed)

Other Identifiers

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UDGEE-SMA

Identifier Type: -

Identifier Source: org_study_id