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A Study of Atherosclerosis in Patients After Radiation Treatment for Breast Cancer

NCT ID: NCT00960401

Last Updated: 2023-11-27

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

20 participants

Study Classification

OBSERVATIONAL

Study Start Date

2005-08-31

Study Completion Date

2014-01-31

Brief Summary

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The purpose of this study is to compare plaque burden in the coronary and carotid arteries 5 years after adjuvant radiotherapy in women with right sided breast cancer vs left sided breast cancer.

Detailed Description

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This study reviews case series of patients with a history of breast cancer treated with radiotherapy for at least five years. The study measures atherosclerosis by using coronary and carotid artery calcium scoring.

Conditions

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Atherosclerosis

Study Design

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Observational Model Type

OTHER

Study Time Perspective

RETROSPECTIVE

Study Groups

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cardiac counseling

10 left sided breast cancer patients 10 right sided breast cancer patients

No interventions assigned to this group

coronary artery evaluation

10 left sided breast cancer 10 right sided breast cancer

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* women dx with ductal carcinoma in situ or breast cancer, stage 0 to stage IIIc, who received conservative surgery and radiotherapy at least 5 years ago
* less than or equal to age 60

Exclusion Criteria

* hx of coronary disease prior to tx of ductal carcinoma in situ or breast cancer
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Winthrop University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Alexander Hindenburg, MD

Role: PRINCIPAL_INVESTIGATOR

Winthrop University Hospital

Locations

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Winthrop University Hospital

Mineola, New York, United States

Site Status

Countries

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United States

References

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Chang M, Suh J, Kirtani V, Dobrescu A, Haas J, Zeldis S, Shayani S, Hindenburg AA. Coronary Calcium Scanning in Patients after Adjuvant Radiation for Early Breast Cancer and Ductal Carcinoma In situ. Front Oncol. 2013 Sep 25;3:253. doi: 10.3389/fonc.2013.00253. eCollection 2013.

Reference Type BACKGROUND
PMID: 24093087 (View on PubMed)

Other Identifiers

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05018

Identifier Type: -

Identifier Source: org_study_id