Cancer Pain Single Nucleotide Polymorphisms (SNPs)

NCT ID: NCT00956878

Last Updated: 2014-12-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

243 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-09-30

Study Completion Date

2012-12-31

Brief Summary

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Cancer pain is common in advanced cancer patients. Opioids are the mainstay of treatment in cancer pain. Responsiveness to and tolerability of opioids is, amongst others, determined by small variations in human DNA. Using blood samples from clinically well-defined cancer pain patients, the investigators are going to analyze single nucleotide polymorphisms (SNPs) in genes that are known to be involved in responsiveness to opioids and sensitivity to pain.

Detailed Description

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Conditions

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Cancer Pain

Keywords

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Cancer Pain SNP

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Cancer Pain Patients

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Cancer pain patients

Exclusion Criteria

* Patients not able to provide informed consent
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Erasmus Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Joost LM Jongen

Dr. J.L.M. Jongen, MD, PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Joost L Jongen, MD PhD

Role: PRINCIPAL_INVESTIGATOR

Erasmus Medical Center

Locations

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Erasmus MC, Centrumlocatie en Daniel den Hoed

Rotterdam, South Holland, Netherlands

Site Status

Countries

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Netherlands

Related Links

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Other Identifiers

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MEC2008-166

Identifier Type: -

Identifier Source: org_study_id