Trial Outcomes & Findings for Medication-overuse Headache: 4 Years Follow up (NCT NCT00918671)

NCT ID: NCT00918671

Last Updated: 2020-12-02

Results Overview

Change in headache days/month after 4 years compared to baseline

Recruitment status

COMPLETED

Target enrollment

60 participants

Primary outcome timeframe

Baseline and after 4 years

Results posted on

2020-12-02

Participant Flow

Inclusion during the period between January 2008 and May 2010

Invited to visit a neurologist, interviewed by telephone, give response by letter, or had headache data available in their hospital records

Participant milestones

Participant milestones
Measure
Medication-overuse Headache
Chronic daily headache combined with medication overuse
Overall Study
STARTED
60
Overall Study
COMPLETED
60
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Medication-overuse Headache: 4 Years Follow up

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Medication-overuse Headache
n=60 Participants
Chronic daily headache combined with medication overuse
Age, Categorical
<=18 years
0 Participants
n=5 Participants
Age, Categorical
Between 18 and 65 years
60 Participants
n=5 Participants
Age, Categorical
>=65 years
0 Participants
n=5 Participants
Age, Continuous
40.6 years
STANDARD_DEVIATION 10.96 • n=5 Participants
Sex: Female, Male
Female
37 Participants
n=5 Participants
Sex: Female, Male
Male
23 Participants
n=5 Participants

PRIMARY outcome

Timeframe: Baseline and after 4 years

Change in headache days/month after 4 years compared to baseline

Outcome measures

Outcome measures
Measure
Medication-overuse Headache
n=60 Participants
Chronic daily headache combined with medication overuse
Change in Headache Days/Month After 4 Years Compared to Baseline
6.6 headache days/month
Standard Deviation 9.87

SECONDARY outcome

Timeframe: Baseline and after 4 years' of follow-up

Outcome measures

Outcome measures
Measure
Medication-overuse Headache
n=60 Participants
Chronic daily headache combined with medication overuse
Change of Medication Days/Month Compared to Baseline
9.53 medication days/month
Standard Deviation 9.99

Adverse Events

Medication-overuse Headache

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Professor Knut Hagen

NTNU

Phone: +4772575080

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place