Using Duke Activity Status Index (DASI) to Select Optimal Cardiac Stress Tests

NCT ID: NCT00907855

Last Updated: 2011-11-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-04-30

Brief Summary

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Cardiac stress testing with functional nuclear imaging is an invaluable technique in the diagnostic and prognostic evaluation of patients with known or suspected ischemic heart disease. Selection of the appropriate type of nuclear stress test: exercise stress Myocardial Perfusion Imaging (MPI) versus pharmacologic stress MPI is crucial for not only diagnostic accuracy and prognostic evaluation, but also for sound clinical decisions and resource utilization.

The Duke Activity Status Index (DASI) is a 12-item questionnaire that utilized self-reported physical work capacity to estimate peak metabolic equivalents (METs) and has been shown to be a valid measurement of functional capacity. The investigators hypothesized that the DASI may be the screening tool that evaluates functional capacity and guides selection of the optimal stress MPI study.

Detailed Description

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Conditions

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Ischemic Heart Disease

Keywords

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Ischemic Heart Disease Duke Activity Status Index Stress Myocardial Perfusion Imaging

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Age \> 18

Exclusion Criteria

* None
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Astellas Pharma Inc

INDUSTRY

Sponsor Role collaborator

NYU Langone Health

OTHER

Sponsor Role lead

Responsible Party

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Lawrence Phillips, MD

Director, Nuclear Cardiology

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Jennifer H. Mieres, MD

Role: PRINCIPAL_INVESTIGATOR

Division of Cardiology, New York University School of Medicine

Lawrence Phillips, MD

Role: STUDY_DIRECTOR

Division of Cardiology, New York University School of Medicine

Locations

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Nuclear Cardiology/Stress Lab, NYU Cardiology Division

New York, New York, United States

Site Status

Countries

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United States

References

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Shaw LJ, Olson MB, Kip K, Kelsey SF, Johnson BD, Mark DB, Reis SE, Mankad S, Rogers WJ, Pohost GM, Arant CB, Wessel TR, Chaitman BR, Sopko G, Handberg E, Pepine CJ, Bairey Merz CN. The value of estimated functional capacity in estimating outcome: results from the NHBLI-Sponsored Women's Ischemia Syndrome Evaluation (WISE) Study. J Am Coll Cardiol. 2006 Feb 7;47(3 Suppl):S36-43. doi: 10.1016/j.jacc.2005.03.080.

Reference Type BACKGROUND
PMID: 16458169 (View on PubMed)

Hlatky MA, Boineau RE, Higginbotham MB, Lee KL, Mark DB, Califf RM, Cobb FR, Pryor DB. A brief self-administered questionnaire to determine functional capacity (the Duke Activity Status Index). Am J Cardiol. 1989 Sep 15;64(10):651-4. doi: 10.1016/0002-9149(89)90496-7.

Reference Type BACKGROUND
PMID: 2782256 (View on PubMed)

Other Identifiers

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NYU DASI 08-713

Identifier Type: -

Identifier Source: org_study_id