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Exercise Pulseoximetry for Pre-flight Evaluation of Chronic Obstructive Pulmonary Disease (COPD) Patients

NCT ID: NCT00896584

Last Updated: 2010-11-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-05-31

Study Completion Date

2010-11-30

Brief Summary

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Some patients with chronic obstructive pulmonary disease (COPD) need supplementary oxygen during air travel. Guidelines issued by The British Thoracic Society (BTS) for pre-flight evaluation do not discriminate sufficiently between those who need supplementary oxygen during flight, and those who can do without. Previous studies have indicated that decreasing hemoglobin oxygen saturation during exercise may predict in-flight hypoxemia. The objective of the present study is to examine if adding exercise oxygen desaturation to the BTS algorithm will better predict requirements for in-flight supplementary oxygen.

Detailed Description

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The British Thoracic Society (BTS) guidelines on pre-flight evaluation for patients with chronic respiratory disease is based on an algorithm where arterial oxygen saturation is the discriminating factor. It has recently been shown that this algorithm does not discriminate sufficiently between patients who need pre-flight evaluation and maybe supplementary oxygen during air travel, and those who can travel by air without supplemental oxygen or further evaluation. Studies have also shown that exercise desaturation may predict in-flight hypoxemia. The objective of the present study is to examine if inclusion of arterial oxygen saturation measured by pulseoximetry during exercise in the BTS algorithm, will increase the sensitivity and specificity of the BTS pre-flight evaluation guidelines.The study also include questionnaires on symptoms during air travel carried out before ande after the pre-flight evaluation.

Conditions

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Chronic Obstructive Pulmonary Disease Hypoxemia

Keywords

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Chronic obstructive pulmonary disease Hypoxemia Pre-flight evaluation Hypobaria COPD Pulseoximetry Air travel Exercise desaturation

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* patients with COPD who have performed a hypoxia altitude simulation test
* able to perform the 6-minute walking test

Exclusion Criteria

* unstable angina
* uncontrolled hypertension
* uncontrolled arrythmia
* patients with long-term oxygen treatment
Minimum Eligible Age

40 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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LHL Helse

OTHER

Sponsor Role lead

Responsible Party

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Glittreklinikken

Principal Investigators

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Anne Edvardsen, MSc

Role: PRINCIPAL_INVESTIGATOR

LHL Helse

Morten S Ryg, Dr philos

Role: STUDY_DIRECTOR

LHL Helse

Locations

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Glittreklinikken

Hakadal, Hakadal, Norway

Site Status

Countries

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Norway

References

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Akero A, Christensen CC, Edvardsen A, Ryg M, Skjonsberg OH. Pulse oximetry in the preflight evaluation of patients with chronic obstructive pulmonary disease. Aviat Space Environ Med. 2008 May;79(5):518-24. doi: 10.3357/asem.2120.2008.

Reference Type BACKGROUND
PMID: 18500050 (View on PubMed)

Akero A, Christensen CC, Edvardsen A, Skjonsberg OH. Hypoxaemia in chronic obstructive pulmonary disease patients during a commercial flight. Eur Respir J. 2005 Apr;25(4):725-30. doi: 10.1183/09031936.05.00093104.

Reference Type BACKGROUND
PMID: 15802350 (View on PubMed)

British Thoracic Society Standards of Care Committee. Managing passengers with respiratory disease planning air travel: British Thoracic Society recommendations. Thorax. 2002 Apr;57(4):289-304. doi: 10.1136/thorax.57.4.289. No abstract available.

Reference Type BACKGROUND
PMID: 11923546 (View on PubMed)

Edvardsen A, Ryg M, Akero A, Christensen CC, Skjonsberg OH. COPD and air travel: does hypoxia-altitude simulation testing predict in-flight respiratory symptoms? Eur Respir J. 2013 Nov;42(5):1216-23. doi: 10.1183/09031936.00157112. Epub 2012 Dec 20.

Reference Type DERIVED
PMID: 23258777 (View on PubMed)

Other Identifiers

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S-08640b (REK)

Identifier Type: -

Identifier Source: secondary_id

2541 (Biobank)

Identifier Type: -

Identifier Source: secondary_id

2008/2/0079 (HelseRehab)

Identifier Type: -

Identifier Source: secondary_id

GK-40/3

Identifier Type: -

Identifier Source: org_study_id