Vitamin D Supplementation in Childhood Atopic Dermatitis
NCT ID: NCT00879424
Last Updated: 2016-12-22
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
107 participants
INTERVENTIONAL
2009-02-28
2009-05-31
Brief Summary
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Detailed Description
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Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
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1
cholecalciferol (vitamin D)
1000 IU once daily x 1 month
Experimental group will receive Ddrops (Toronto, Canada). Placebo group will receive placebo drops.
2
Placebo
1000 IU once daily x 1 month
Experimental group will receive Ddrops (Toronto, Canada). Placebo group will receive placebo drops.
Interventions
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cholecalciferol (vitamin D)
1000 IU once daily x 1 month
Experimental group will receive Ddrops (Toronto, Canada). Placebo group will receive placebo drops.
Placebo
1000 IU once daily x 1 month
Experimental group will receive Ddrops (Toronto, Canada). Placebo group will receive placebo drops.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* AD rated 10-72 by EASI scale
* Wintertime onset or exacerbation of AD
Exclusion Criteria
* History of summertime onset or exacerbation of AD
* History of underlying illness causing immunosuppression within the past 2 years (eg. hematologic malignancies)
* Medications causing iatrogenic immunosuppression (eg. cyclosporine; azathioprine, oral steroids) taken within the past month
* Parathyroid disease
* Acute or chronic renal disease
* Hypercalcemia or hypocalcemia
* Thyroid disease
* History of osteomalacia or Paget's disease of bone
* History of malabsorption (eg cystic fibrosis)
* Planned trip to sunny climate during the one-month study
2 Years
17 Years
ALL
No
Sponsors
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Massachusetts General Hospital
OTHER
Responsible Party
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Carlos A. Camargo, Jr.
Physician
Principal Investigators
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Carlos A. Camargo, MD, DrPH
Role: PRINCIPAL_INVESTIGATOR
Massachusetts General Hospital
Locations
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National Dermatology Center
Ulaanbaatar, , Mongolia
Countries
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References
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Sidbury R, Sullivan AF, Thadhani RI, Camargo CA Jr. Randomized controlled trial of vitamin D supplementation for winter-related atopic dermatitis in Boston: a pilot study. Br J Dermatol. 2008 Jul;159(1):245-7. doi: 10.1111/j.1365-2133.2008.08601.x. Epub 2008 Jul 1. No abstract available.
Camargo CA Jr, Ganmaa D, Sidbury R, Erdenedelger Kh, Radnaakhand N, Khandsuren B. Randomized trial of vitamin D supplementation for winter-related atopic dermatitis in children. J Allergy Clin Immunol. 2014 Oct;134(4):831-835.e1. doi: 10.1016/j.jaci.2014.08.002.
Huey SL, Acharya N, Silver A, Sheni R, Yu EA, Pena-Rosas JP, Mehta S. Effects of oral vitamin D supplementation on linear growth and other health outcomes among children under five years of age. Cochrane Database Syst Rev. 2020 Dec 8;12(12):CD012875. doi: 10.1002/14651858.CD012875.pub2.
Other Identifiers
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CeDAR-01
Identifier Type: -
Identifier Source: org_study_id