Risk Factors for Postpartum Psychosis

NCT ID: NCT00872313

Last Updated: 2014-01-14

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 4000 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2009-02-28
• Study Completion Date: 2012-08-31

Brief Summary

A range of psychological disorders occur in women in the postpartum period. These include "the blues", which occurs in the first days after birth and which is very common and self-limiting; severe psychoses often associated with mania or bipolar illness, occurring in the first weeks after birth; and mild to moderate depression, occurring weeks to months after birth. Studies have been done focused on postpartum psychosis using a retrospective investigation, which gave only a limited material on the prevalence of psychological disorders in postpartum women. The investigators hypothesized that different pathways to psychosis function as the risk factors which may be overlapped, truly independent, mediating, or moderating, in new mothers who are at high risk and/or during the early period of delivery. In addition, the investigators purposed that the temporal sequence of biological, social and demographic variables are also the potential factors contributing to the development of postpartum psychosis.

Conditions

Postpartum Period; Psychosis

Study Design

• Observational Model Type: CASE_ONLY
• Study Time Perspective: PROSPECTIVE

Study Groups

1

Psychoses within the first 3 months postpartum

No interventions assigned to this group

2

Psychoses \> 3 months to 6 months postpartum

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• Pregnant women
• Chinese

Exclusion Criteria

• Age < 18 years or > 50 years
• Gestational age < 32 weeks

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 50 Years
• Eligible Sex: FEMALE
• Accepts Healthy Volunteers: No

Sponsors

Nanjing Medical University

OTHER

Sponsor Role: lead

Responsible Party

Fu Zhou Wang

Dr

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

XiaoFeng Shen, MD

Role: STUDY_DIRECTOR

Nanjing Medical University

Locations

Nanjing Maternal and Child Health Care Hospital

Nanjing, Jiangsu, China

Countries

China

Other Identifiers

NJFY09102M107

Identifier Type: -

Identifier Source: secondary_id

NMU-200903-MZ003

Identifier Type: -

Identifier Source: org_study_id