Tolerance and Prebiotic Activity of Arabinoxylan-Oligosaccharides in Healthy Subjects

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-10-31

Study Completion Date

2008-06-30

Brief Summary

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The purpose of the study is to evaluate the tolerance of a higher dose of arabinoxylan-oligosaccharides (AXOS) and their prebiotic activity in healthy subjects.

Detailed Description

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Conditions

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Healthy

Keywords

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tolerance prebiotic gastrointestinal effects

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Interventions

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arabinoxylan-oligosaccharides (AXOS)

intake period: 3 weeks, 10 g/day

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* healthy
* 18-45 years
* regular eating pattern

Exclusion Criteria

* gastrointestinal complaints
* antibiotic intake
* medication influencing gut transit or microbiota
* abdominal surgery
* pregnancy

Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Responsible Party

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Katholieke Universiteit Leuven

Principal Investigators

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Kristin Verbeke, PhD

Role: STUDY_DIRECTOR

KU Leuven

Locations

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Department of Gastrointestinal Research, Laboratory Digestion and Absorption

Leuven, Leuven, Belgium

Site Status

Countries

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Belgium

References

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Cloetens L, De Preter V, Swennen K, Broekaert WF, Courtin CM, Delcour JA, Rutgeerts P, Verbeke K. Dose-response effect of arabinoxylooligosaccharides on gastrointestinal motility and on colonic bacterial metabolism in healthy volunteers. J Am Coll Nutr. 2008 Aug;27(4):512-8. doi: 10.1080/07315724.2008.10719733.

Reference Type BACKGROUND

PMID: 18978172 (View on PubMed)

Other Identifiers

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AXOS 002

Identifier Type: -

Identifier Source: org_study_id