Trial Outcomes & Findings for A Multi - Center Study Of PET Imaging With [F-18] FLT & [F-18] FDG in Cancer Patients for Treatment Evaluation (NCT NCT00847509)

NCT ID: NCT00847509

Last Updated: 2013-09-27

Results Overview

The sponsor decided not to further develop \[F-18\]FLT. Therefore, no further analysis was performed.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

49 participants

Primary outcome timeframe

3-5 weeks after the start of radiation or chemo radio therapy

Results posted on

2013-09-27

Participant Flow

A total of 49 patients were enrolled and 38 patients received investiational product.

Participant milestones

Participant milestones
Measure
[F-18]FLT PET Scan
Open label, nonrandomized, uncontrolled, single group assignment, multi-center clinical trial to evaluate \[F-18\] FLT as a PET imaging tool in cancer patients clinically scheduled for treatment with radiation or radiation - chemotherapy. Standard \[F-18\] FDG PET will be the active comparator.
Overall Study
STARTED
49
Overall Study
COMPLETED
38
Overall Study
NOT COMPLETED
11

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

A Multi - Center Study Of PET Imaging With [F-18] FLT & [F-18] FDG in Cancer Patients for Treatment Evaluation

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
[F-18]FLT Scan
n=49 Participants
Age, Categorical
<=18 years
0 Participants
n=5 Participants
Age, Categorical
Between 18 and 65 years
27 Participants
n=5 Participants
Age, Categorical
>=65 years
22 Participants
n=5 Participants
Age Continuous
64.67 years
STANDARD_DEVIATION 10.38 • n=5 Participants
Sex: Female, Male
Female
26 Participants
n=5 Participants
Sex: Female, Male
Male
23 Participants
n=5 Participants
Region of Enrollment
United States
49 participants
n=5 Participants

PRIMARY outcome

Timeframe: 3-5 weeks after the start of radiation or chemo radio therapy

The sponsor decided not to further develop \[F-18\]FLT. Therefore, no further analysis was performed.

Outcome measures

Outcome data not reported

Adverse Events

[F-18]FLT PET Scan

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Edward M. Aten, M.D.

Certus International, Inc.

Phone: 603.627.1212

Results disclosure agreements

  • Principal investigator is a sponsor employee The restriction on the PI is that the sponsor can review results communication prior to public release and can embargo communications regarding trial results.
  • Publication restrictions are in place

Restriction type: OTHER