Marathon, Genetics, Inflammation and the Cardiovascular System: MAGIC-Trial
NCT ID: NCT00845286
Last Updated: 2016-03-17
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
162 participants
INTERVENTIONAL
2008-09-30
2014-08-31
Brief Summary
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Detailed Description
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We aim to define the critical role of inflammatory markers and cardiovascular risc factors as a predictor of an increased risk for myocardial and endothelial dysfunction in marathon runners.
Diagnostic tools include measurements of augmentation index (AIx), arteriolar-venular ratio (AVR) and, for the first time, 2D and 3D echocardiographic measurements such as TDI-imaging and speckle tracking. Inflammatory markers include c-reactive protein (CRP), interleukins and tumor necrosis factor. Additionally, cardiovascular markers are measured. All variations are analysed on the basis of genotype characteristics/polymorphisms.
Conditions
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Study Design
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NON_RANDOMIZED
SINGLE_GROUP
PREVENTION
NONE
Interventions
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Munich Marathon
42,195 km marathon run
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* insulin dependent diabetes mellitus
* multi drug therapy
* GFR\<60ml/min.
30 Years
60 Years
MALE
Yes
Sponsors
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Technical University of Munich
OTHER
Responsible Party
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Locations
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Department of Prevention and Sports medicine
Munich, Bavaria, Germany
Countries
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Other Identifiers
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1807/07-II
Identifier Type: -
Identifier Source: org_study_id
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