Evaluation of the Cardioblate Closure Device in Facilitating Occlusion of the Left Atrial Appendage

NCT ID: NCT00841529

Last Updated: 2012-10-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

PHASE2

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-03-31

Study Completion Date

2010-06-30

Brief Summary

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The purpose of this study is to evaluate the performance of the Cardioblate Closure Device to occlude the LAA

Detailed Description

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Conditions

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Left Atrial Appendage Occlusion

Keywords

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left atrial appendage LAA atrial fibrillation AF

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Interventions

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Medtronic LAA Occlusion Device

Placement of the occlusion band on the LAA

Intervention Type DEVICE

Other Intervention Names

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Medtronic Cardioblate Closure Left Atrial Appendage Occlusion Device

Eligibility Criteria

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Inclusion Criteria

* Subject is greater than or equal to 18 years of age and less than or equal to 80 years of age
* Concomitant indication for cardiac surgery for one or more of the following:mitral valve repair or replacement, aortic valve repair or replacement, tricuspid valve repair or replacement, CABG (\>=60 years of age), CABG (\< 60 years of age with a history of atrial fibrillation), surgical ablation or Maze procedure
* The subject is willing and able to provide written informed consent and comply with study requirements
* The subject is not contra-indicated for intra-operative transesophageal echocardiogram (TEE)

Exclusion Criteria

* Thrombus in the LAA and/or left atrium
* Prior LAA isolation attempts
* Subject is unable to take an anticoagulant during the study follow-up period
* Subject is undergoing an emergency cardiac procedure
* Life expectancy of less than 12 months
* Pregnancy or desire to be pregnant within the 12 months of the study procedure
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medtronic Cardiovascular

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Patrick McCarthy, MD

Role: STUDY_CHAIR

Northwestern University

Locations

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Eisenhower Medical Center

Rancho Mirage, California, United States

Site Status

Yale University School of Medicine

New Haven, Connecticut, United States

Site Status

Northwestern Memorial Hospital

Chicago, Illinois, United States

Site Status

Oklahoma Heart Hospital

Oklahoma City, Oklahoma, United States

Site Status

Aurora St. Luke's Medical Center

Milwaukee, Wisconsin, United States

Site Status

Countries

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United States

Other Identifiers

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D02940

Identifier Type: -

Identifier Source: org_study_id