Trial Outcomes & Findings for Changes in Ectopic Fat Following Surgically Induced Weight Loss (NCT NCT00840307)

NCT ID: NCT00840307

Last Updated: 2017-12-13

Results Overview

Pancreatic triglyceride (fat) content measured by the magnetic resonance spectroscopy (MRS) technique in volunteers with a wide range of body mass index (BMI).

Recruitment status

COMPLETED

Target enrollment

20 participants

Primary outcome timeframe

months after the first band inflation

Results posted on

2017-12-13

Participant Flow

Participant milestones

Participant milestones
Measure
Patient With Gastric Band
20 patients recruited from bariatric surgery clinic followed-up before surgery and for 12 months after inflation of the gastric band.
Overall Study
STARTED
20
Overall Study
COMPLETED
16
Overall Study
NOT COMPLETED
4

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Changes in Ectopic Fat Following Surgically Induced Weight Loss

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Patient With Gastric Band
n=20 Participants
20 patients recruited from bariatric surgery clinic followed-up before surgery and for 12 months after inflation of the gastric band.
Age, Categorical
<=18 years
0 Participants
n=5 Participants
Age, Categorical
Between 18 and 65 years
20 Participants
n=5 Participants
Age, Categorical
>=65 years
0 Participants
n=5 Participants
Age, Continuous
49.1 years
STANDARD_DEVIATION 11.0 • n=5 Participants
Sex: Female, Male
Female
17 Participants
n=5 Participants
Sex: Female, Male
Male
3 Participants
n=5 Participants
Region of Enrollment
United States
20 Participants
n=5 Participants

PRIMARY outcome

Timeframe: months after the first band inflation

Pancreatic triglyceride (fat) content measured by the magnetic resonance spectroscopy (MRS) technique in volunteers with a wide range of body mass index (BMI).

Outcome measures

Outcome measures
Measure
Patient With Gastric Band
n=16 Participants
20 patients recruited from bariatric surgery clinic followed-up before surgery and for 12 months after inflation of the gastric band.
Pancreatic and Liver Triglyceride (Fat) Content
Pancreatic fat
6.44 percent
Interval 1.75 to 25.02
Pancreatic and Liver Triglyceride (Fat) Content
Liver fat
2.08 percent
Interval 1.43 to 3.63

Adverse Events

Patient With Gastric Band

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. Ildiko Lingvay

UT Southwestern Medical Center

Phone: 214-648-2779

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place