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Comparative Efficacy and Safety of Benzoyl Peroxide Used in Combination With Clindamycin vs. Benzoyl Peroxide Used in Combination With Clindamycin and Doxycycline in the Treatment of Moderate Acne

NCT ID: NCT00837213

Last Updated: 2017-05-25

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

33 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-08-31

Study Completion Date

2008-08-31

Brief Summary

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To compare the efficacy and safety of Benzoyl peroxide used in combination with clindamycin vs. Benzoyl peroxide used in combination with clindamycin and doxycycline in the treatment of moderate acne

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Detailed Description

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To compare the efficacy and safety of Benzoyl peroxide used in combination with clindamycin vs. Benzoyl peroxide used in combination with clindamycin and doxycycline once daily in the treatment of moderate acne

Conditions

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Acne

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Investigators

Study Groups

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BPO with clindamycin foam

Benzoyl peroxide (BPO) wash with clindamycin foam

Group Type ACTIVE_COMPARATOR

Benzoyl peroxide with clindamycin

Intervention Type DRUG

Benzoyl peroxide wash - Clindamycin foam

BPO + clindamycin foam + doxycycline

Benzoyl peroxide (BPO) wash with clindamycin foam and doxycycline capsules

Group Type ACTIVE_COMPARATOR

Benzoyl peroxide with clindamycin and doxycycline

Intervention Type DRUG

Benzoyl peroxide wash - Clindamycin foam - Doxycycline capsules

Interventions

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Benzoyl peroxide with clindamycin

Benzoyl peroxide wash - Clindamycin foam

Intervention Type DRUG

Benzoyl peroxide with clindamycin and doxycycline

Benzoyl peroxide wash - Clindamycin foam - Doxycycline capsules

Intervention Type DRUG

Other Intervention Names

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Acne Acne

Eligibility Criteria

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Inclusion Criteria

* Male or female subjects with acne vulgaris . Able to understand the requirements of the study and sign informed consent/HIPAA authorization forms.

Exclusion Criteria

* Known hypersensitivity to any of the components of the study drugs or used of prohibited medications or any medical condition that contraindicate the subject's participation in the clinical study
Minimum Eligible Age

16 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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GlaxoSmithKline

INDUSTRY

Sponsor Role collaborator

Stiefel, a GSK Company

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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GSK Clinical Trials

Role: STUDY_DIRECTOR

GlaxoSmithKline

Locations

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Center for Dermatology, Cosmetic and Laser Surgery

Fremont, California, United States

Site Status

Las Vegas Skin & Cancer Clinic

Las Vegas, Nevada, United States

Site Status

Countries

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United States

Other Identifiers

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EVF0701

Identifier Type: -

Identifier Source: org_study_id

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