A Study to Assess Indices of SNAP vs VISTA on Surgical Patients Undergoing General Anesthesia

NCT ID: NCT00829803

Last Updated: 2021-11-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-02-28

Study Completion Date

2011-01-31

Brief Summary

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Establish the range of index values for the SNAP II corresponding to each anesthetic state studied.

Detailed Description

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Index values for the SNAP II monitor will be identified with each corresponding anesthetic state studied.

Conditions

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Anesthesia, General

Keywords

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To acquire developmental data to prospectively support SNAP II index ranges at the studied anesthetic states.

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

DOUBLE

Participants Caregivers

Study Groups

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SNAP Monitor EEG signals

Group Type EXPERIMENTAL

SNAP monitor; Bispectral Index Monitor (BIS Monitor)

Intervention Type DEVICE

Intended to monitor the state of the brain by data acquisition of EEG signals.

BIS Monitor EEG signals (VISTA)

Group Type ACTIVE_COMPARATOR

SNAP monitor; Bispectral Index Monitor (BIS Monitor)

Intervention Type DEVICE

Intended to monitor the state of the brain by data acquisition of EEG signals.

Interventions

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SNAP monitor; Bispectral Index Monitor (BIS Monitor)

Intended to monitor the state of the brain by data acquisition of EEG signals.

Intervention Type DEVICE

Other Intervention Names

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SNAP II monitor BIS Monitor

Eligibility Criteria

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Inclusion Criteria

* Patients scheduled for surgery requiring general anesthesia
* Open or laparoscopic procedures
* Cases anticipated to be less than 4 hours in duration
* In-patient and out-patient subjects
* Patients and cases manageable with LMA. Cases manageable with ET tube are also allowed with the condition that only a minimal dose of short-acting NMBA is used at intubation and not throughout the case.
* Local analgesia at incision site is permitted.
* Males and Females between 18 and 65 years of age, inclusive.
* BMI\<40 and body mass\>41 kg
* Patients who have signed the informed consent.
* Able to receive Informed Consent through subjects native language providing that a native language speaker delivers the Informed Consent.
* ASA Stratification I - III

* ASA stratification \>= IV
* Subject is a prisoner.
* Patients presenting with evidence of recent trauma, active infection, neurological disorder, seizure disorder, dementia or have been diagnosed with Alzheimer's disease
* Subjects with cardiac or gastric pace makers
* Pregnant women as identified by institutional SOP for female of child-bearing age
* Patients that will not sign an informed consent form
* Patients with previous adverse incidents with anesthesia, including awareness
* Patients undergoing surgery on the head or neck
* Subjects currently taking psychoactive medications as part of routine medical care within the past 7 days
* Subjects that require and/or receive any of the psychotherapeutic agents or psychotropic drugs below, in the treatment of mental illness, and have taken such treatment within the past 7 days.
* Benzodiazepines
* MAOI inhibitors
* Selective serotonin reuptake inhibitors (SSRIs)
* Tricyclic antidepressants
* Lithium
* Neuroleptic agents
* Central nervous system stimulants.
* Subjects with a known history of alcohol or narcotic abuse within 6 months prior to screening OR subjects reporting narcotic or narcotic medication use with 24 hours prior to surgery.
* Subjects requiring neurophysiologic monitoring
* Subjects requiring TIVA
* Subjects requiring prolonged use of NMBA beyond dose required for intubation
* Subjects requiring ketamine
* Subjects receiving spinal, epidural, or other nerve blocks
* Subjects having any condition or severe illness that to the Principal Investigator's discretion would interfere with study assessments OR other severe acute or chronic medical or psychiatric condition that may interfere with the interpretation of study results and, in the judgment of the investigator, and would make the subject inappropriate for entry into this study.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Stryker Instruments

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Sergio D Bergese, M.D.

Role: STUDY_CHAIR

Ohio State University

Locations

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University Of Miami

Miami, Florida, United States

Site Status

Northwestern University Feinberg School of Medicine

Chicago, Illinois, United States

Site Status

Beaumont Hospital

Royal Oak, Michigan, United States

Site Status

The Ohio State University Medical Center

Columbus, Ohio, United States

Site Status

Countries

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United States

References

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Bergese SD, Uribe AA, Puente EG, Marcus RL, Krohn RJ, Docsa S, Soto RG, Candiotti KA. A Prospective, Multicenter, Single-Blind Study Assessing Indices of SNAP II Versus BIS VISTA on Surgical Patients Undergoing General Anesthesia. JMIR Res Protoc. 2017 Feb 3;6(2):e15. doi: 10.2196/resprot.6741.

Reference Type DERIVED
PMID: 28159731 (View on PubMed)

Other Identifiers

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SIS-SNAP-2008-01US

Identifier Type: -

Identifier Source: org_study_id