Chronic Pain After Inguinal Hernia Repair

NCT ID: NCT00820131

Last Updated: 2014-12-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

250 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-01-31

Study Completion Date

2014-12-31

Brief Summary

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Chronic pain after inguinal hernia repair has become a major concern. Although tension-free Lichtenstein technique is used and new lightweight meshes have been developed, still up to 40 % of patients complain of some kind of pain even one year after surgery. The necessity of mesh-fixation using sutures, could be causative. However, current data do not provide evidence whether suture fixation in Lichtenstein repair might be the reason for chronic postoperative pain.

A newly developed selfgrip-mesh enables sutureless fixation of the mesh in open inguinal hernia repair. Hereby a polypropylene mesh is combined with a resorbable polylactic-acid gripping system. Thereby the rate of chronic postoperative pain could be decreased.

Two techniques of inguinal hernia repair will be evaluated:

1. open anterior mesh repair using conventional Lichtenstein technique (sutures for mesh-fixation)
2. open anterior mesh repair using a selfgrip mesh (polylactic-acid gripping system for mesh fixation)

Postoperative pain will be evaluated by visual analog scale and Mc Gill pain questionaire at the 10th day, as well as 3 and 15 months postoperatively.

Detailed Description

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Conditions

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Inguinal Hernia Chronic Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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1

Group Type EXPERIMENTAL

selfgrip mesh

Intervention Type PROCEDURE

inguinal hernia repair using a selfgrip mesh

2

Group Type ACTIVE_COMPARATOR

lightweight mesh with suture fixation

Intervention Type PROCEDURE

inguinal hernia repair using a lightweight mesh with suture fixation

Interventions

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selfgrip mesh

inguinal hernia repair using a selfgrip mesh

Intervention Type PROCEDURE

lightweight mesh with suture fixation

inguinal hernia repair using a lightweight mesh with suture fixation

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* primary unilateral inguinal hernia
* 18 years and older

Exclusion Criteria

* bilateral hernia
* recurrent hernia
* incarcerated hernia
* malignant disease within the last 5 years
* not able to understand the questionaire
Minimum Eligible Age

18 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medical University of Vienna

OTHER

Sponsor Role lead

Responsible Party

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Medical University of Vienna

Principal Investigators

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Gerhard Prager, MD

Role: PRINCIPAL_INVESTIGATOR

Medical University of Vienna

Locations

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LKH Feldkirch, Dept. of Surgery

Feldkirch, , Austria

Site Status

Hospital Barmherzige Schwestern

Linz, , Austria

Site Status

LK Weinviertel Mistelbach, Surgical Department

Mistelbach, , Austria

Site Status

KH Göttlicher Heiland

Vienna, , Austria

Site Status

KFJ Hospital, Dept. of Surgery

Vienna, , Austria

Site Status

Medical University of Vienna, Dept. of Surgery

Vienna, , Austria

Site Status

KH Wiener Neustadt, Surgical Department

Wiener Neustadt, , Austria

Site Status

Countries

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Austria

Other Identifiers

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EK MUW 613/2007

Identifier Type: -

Identifier Source: org_study_id