Caloric Restriction and Body Weight in Adults

NCT ID: NCT00808275

Last Updated: 2011-12-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

79 participants

Study Classification

INTERVENTIONAL

Study Start Date

2004-09-30

Study Completion Date

2007-10-31

Brief Summary

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The purpose of this study is to determine the role of

1. dietary calcium in fecal fat loss and the association between lactose maldigestion, dietary calcium level and source, and weight loss induced by caloric restriction.
2. caloric restriction on biomarkers of inflammation and oxidative stress

Detailed Description

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Conditions

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Overweight

Keywords

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dietary calcium weight loss

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Dairy calcium

Diet with dairy calcium sources

Group Type EXPERIMENTAL

Dietary calcium

Intervention Type DIETARY_SUPPLEMENT

Dairy and non-dairy calcium provided as a part of diet in the amounts of 500 mg/day and 1500 mg/day. Diet contained 70% of daily caloric requirements.

Non-dairy calcium

Diet with non-dairy calcium sources

Group Type EXPERIMENTAL

Dietary calcium

Intervention Type DIETARY_SUPPLEMENT

Dairy and non-dairy calcium provided as a part of diet in the amounts of 500 mg/day and 1500 mg/day. Diet contained 70% of daily caloric requirements.

Interventions

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Dietary calcium

Dairy and non-dairy calcium provided as a part of diet in the amounts of 500 mg/day and 1500 mg/day. Diet contained 70% of daily caloric requirements.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* 18 -65 years old
* Healthy

Exclusion Criteria

* Body weight more than 300 lbs (body composition measurement instrument limit) diabetes
* Heart disease
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Vanderbilt University

OTHER

Sponsor Role lead

Responsible Party

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Maciej Buchowski

Research Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Maciej Buchowski, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Vanderbilt University

References

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Buchowski MS, Hongu N, Acra S, Wang L, Warolin J, Roberts LJ 2nd. Effect of modest caloric restriction on oxidative stress in women, a randomized trial. PLoS One. 2012;7(10):e47079. doi: 10.1371/journal.pone.0047079. Epub 2012 Oct 5.

Reference Type DERIVED
PMID: 23071718 (View on PubMed)

Buchowski MS, Aslam M, Dossett C, Dorminy C, Choi L, Acra S. Effect of dairy and non-dairy calcium on fecal fat excretion in lactose digester and maldigester obese adults. Int J Obes (Lond). 2010 Jan;34(1):127-35. doi: 10.1038/ijo.2009.212. Epub 2009 Oct 13.

Reference Type DERIVED
PMID: 19823185 (View on PubMed)

Other Identifiers

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010590

Identifier Type: -

Identifier Source: org_study_id