Dexamethasone and Analgesic Duration After Supraclavicular Brachial Plexus Blockade

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

44 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-05-31

Study Completion Date

2009-11-30

Brief Summary

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Patients undergoing surgery of the hand often are treated with a nerve block in the shoulder/neck area that provides anesthesia/numbing during surgery. Nerve blocks usually last for a few hours after surgery and provide pain relief for this period. It may be possible to extend the duration of anesthesia by using a steroid, which has anti-inflammtory properties. This study will compare the duration of the nerve block when dexamethasone (steroid) is added to the anesthetic injected around the nerve.

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Detailed Description

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Conditions

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Anesthesia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Caregivers Investigators

Study Groups

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1

Dexamethasone 8mg added to routine local anesthetic during brachial plexus blockade.

Group Type EXPERIMENTAL

Dexamethasone

Intervention Type DRUG

Dexamethasone 8 milligrams (liquid) will be added to standard anesthetic solution administered during routine brachial plexus nerve blockade.

Mepivicaine

Intervention Type DRUG

Standard anesthetic solution administered during routine brachial plexus nerve blockade.

2

Routine anesthetic solution (30 cc 1.5% mepivicaine) used during brachial plexus blockade.

Group Type ACTIVE_COMPARATOR

Mepivicaine

Intervention Type DRUG

Standard anesthetic solution administered during routine brachial plexus nerve blockade.

Interventions

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Dexamethasone

Dexamethasone 8 milligrams (liquid) will be added to standard anesthetic solution administered during routine brachial plexus nerve blockade.

Intervention Type DRUG

Mepivicaine

Standard anesthetic solution administered during routine brachial plexus nerve blockade.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

1. Patients having unilateral hand or forearm surgery under Supraclavicular brachial plexus blockade.
2. ASA I-III
3. Age 18-60
4. BMI \< 35

Exclusion Criteria

1. Patients with a known history of hypersensitivity to local anesthetics and dexamethasone.
2. Contra-indication to regional anesthesia/ supraclavicular brachial plexus blockade e.g. bleeding diathesis, coagulopathy.
3. Peripheral neuropathy.
4. Peptic ulcer disease.
5. Diabetes Mellitus.
6. Inability to give informed consent.

Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No