French Study In ICU Patients Treated With Tigecycline

NCT ID: NCT00799591

Last Updated: 2011-12-19

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

156 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-09-30

Study Completion Date

2010-05-31

Brief Summary

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This study will describe clinical outcome and safety data collected prospectively in subjects hospitalized in an intensive care unit (ICU) presenting with an infection for which treatment with tigecycline, alone or in combination, is planned. Data will be collected only from subjects providing informed consent.

Detailed Description

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Healthcare visit.

Extension Rationale:

In order to perform the necessary corrective actions required and to secure database consistency, we request an extension for posting of Basic Results due 26-May-2011 for protocol 3074A1-4448 (B1811030), NCT00799591. Our proposed submission date is 14-Sept-2011.

Pfizer acquired Wyeth on October 16, 2009. With regard to this study, our reconciliation of data identified some discrepancies in data listed in the Project database (managed by the CRO) and the Safety Database (managed by Pfizer). We are taking corrective action which involves: sending queries to investigators, collecting corrective signed forms, and implementing changes within the database. We are requesting this extension to complete that work so that the data can be treated as final and the CSR can be completed.

Conditions

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Bacterial Infections

Keywords

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Registre MONTRAVERS

Study Design

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Study Time Perspective

PROSPECTIVE

Study Groups

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1

Intensive Care

Observational study so no intervention in the patient.

Intervention Type OTHER

Observational study so no intervention in the patient.

Interventions

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Observational study so no intervention in the patient.

Observational study so no intervention in the patient.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Adult men and women (18 years).
* Subjects hospitalized in a medical or surgical intensive care unit (ICU) (on the day of enrolment in the study).
* Subjects treated with tigecycline (first, second or third line), said treatment freely chosen by the participating physician, prior to enrollment in the study.

Exclusion Criteria

* Subjects participating in another biomedical research study.
* Patient (or legal representative) who has not dated or signed informed consent document.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Wyeth is now a wholly owned subsidiary of Pfizer

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Pfizer CT.gov Call Center

Role: STUDY_DIRECTOR

Pfizer

Locations

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Pfizer Investigational Site

Paris, , France

Site Status

Countries

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France

References

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Bassetti M, Eckmann C, Bodmann KF, Dupont H, Heizmann WR, Montravers P, Guirao X, Capparella MR, Simoneau D, Sanchez Garcia M. Prescription behaviours for tigecycline in real-life clinical practice from five European observational studies. J Antimicrob Chemother. 2013 Jul;68 Suppl 2:ii5-14. doi: 10.1093/jac/dkt140.

Reference Type DERIVED
PMID: 23772047 (View on PubMed)

Guirao X, Sanchez Garcia M, Bassetti M, Bodmann KF, Dupont H, Montravers P, Heizmann WR, Capparella MR, Simoneau D, Eckmann C. Safety and tolerability of tigecycline for the treatment of complicated skin and soft-tissue and intra-abdominal infections: an analysis based on five European observational studies. J Antimicrob Chemother. 2013 Jul;68 Suppl 2:ii37-44. doi: 10.1093/jac/dkt143.

Reference Type DERIVED
PMID: 23772045 (View on PubMed)

Montravers P, Bassetti M, Dupont H, Eckmann C, Heizmann WR, Guirao X, Garcia MS, Capparella MR, Simoneau D, Bodmann KF. Efficacy of tigecycline for the treatment of complicated skin and soft-tissue infections in real-life clinical practice from five European observational studies. J Antimicrob Chemother. 2013 Jul;68 Suppl 2:ii15-24. doi: 10.1093/jac/dkt141.

Reference Type DERIVED
PMID: 23772042 (View on PubMed)

Related Links

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Other Identifiers

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B1811030

Identifier Type: -

Identifier Source: secondary_id

3074A1-4448

Identifier Type: -

Identifier Source: org_study_id