Trial Outcomes & Findings for Outreach for Patients With Uncompleted Colorectal Cancer Screening Orders (NCT NCT00793455)

NCT ID: NCT00793455

Last Updated: 2011-12-01

Results Overview

We reviewed electronic health records of participants 3 months post randomization to ascertain outcome. We looked for one or both of the following (1) note in free text MD note documenting receipt of one form of colorectal cancer (CRC) screening during study period (2)lab results from fecal occult blood test, sigmoidoscopy, or colonoscopy. Participants were categorized as completing CRC screening if there was a lab result or physician note located in chart during study period. If no note or lab result was found in chart, then the participant was categorized as not completing CRC screening.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

628 participants

Primary outcome timeframe

3 months post randomization

Results posted on

2011-12-01

Participant Flow

This trial took place at a large urban academic primary care internal medicine practice in Chicago, IL. This trial was enrolling patients between October 2008 and May 2009.

We used data contained in the clinic's electronic health record to identify eligible patients. All eligible patients were randomly assigned in equal numbers to either the control or intervention arms. All eligible patients were randomized and assigned to groups until we reached target study size.

Participant milestones

Participant milestones
Measure
Intervention Group
Participants assigned to this group received a one-time educational intervention within one week of randomization. Educational intervention consisted of a letter from patient's physician, a brochure about colorectal cancer screening, and a DVD about colorectal cancer screening.
Usual Care Control Group
Participants in this arm will receive normal care until outcome assessment is performed at 6 months following the placement of the order for the preventive service. They will be sent a letter reminding them to obtain the ordered preventive service test.
Overall Study
STARTED
314
314
Overall Study
COMPLETED
314
314
Overall Study
NOT COMPLETED
0
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Outreach for Patients With Uncompleted Colorectal Cancer Screening Orders

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Intervention Group
n=314 Participants
Participants assigned to this group received a one-time educational intervention within one week of randomization. Educational intervention consisted of a letter from patient's physician, a brochure about colorectal cancer screening, and a DVD about colorectal cancer screening.
Usual Care Control Group
n=314 Participants
Participants in this arm will receive normal care until outcome assessment is performed at 6 months following the placement of the order for the preventive service. They will be sent a letter reminding them to obtain the ordered preventive service test.
Total
n=628 Participants
Total of all reporting groups
Age Continuous
57.90 years
STANDARD_DEVIATION 7.1 • n=5 Participants
58.03 years
STANDARD_DEVIATION 6.6 • n=7 Participants
58.0 years
STANDARD_DEVIATION 6.9 • n=5 Participants
Sex: Female, Male
Female
197 Participants
n=5 Participants
192 Participants
n=7 Participants
389 Participants
n=5 Participants
Sex: Female, Male
Male
117 Participants
n=5 Participants
122 Participants
n=7 Participants
239 Participants
n=5 Participants
Race/Ethnicity, Customized
White
144 participants
n=5 Participants
132 participants
n=7 Participants
276 participants
n=5 Participants
Race/Ethnicity, Customized
Black
79 participants
n=5 Participants
77 participants
n=7 Participants
156 participants
n=5 Participants
Race/Ethnicity, Customized
Hispanic
9 participants
n=5 Participants
14 participants
n=7 Participants
23 participants
n=5 Participants
Race/Ethnicity, Customized
Other/unknown
82 participants
n=5 Participants
91 participants
n=7 Participants
173 participants
n=5 Participants
Region of Enrollment
United States
314 participants
n=5 Participants
314 participants
n=7 Participants
628 participants
n=5 Participants
Number of visits in past 2 years
1-2
69 Participants
n=5 Participants
79 Participants
n=7 Participants
148 Participants
n=5 Participants
Number of visits in past 2 years
3
80 Participants
n=5 Participants
79 Participants
n=7 Participants
159 Participants
n=5 Participants
Number of visits in past 2 years
4
54 Participants
n=5 Participants
48 Participants
n=7 Participants
102 Participants
n=5 Participants
Number of visits in past 2 years
>=5
111 Participants
n=5 Participants
108 Participants
n=7 Participants
219 Participants
n=5 Participants
Colorectal Cancer (CRC) screening history
Ever screened
22 Participants
n=5 Participants
24 Participants
n=7 Participants
46 Participants
n=5 Participants
Colorectal Cancer (CRC) screening history
Never screened
292 Participants
n=5 Participants
290 Participants
n=7 Participants
582 Participants
n=5 Participants
Insurance Status
Private
245 Participants
n=5 Participants
236 Participants
n=7 Participants
481 Participants
n=5 Participants
Insurance Status
Medicare
56 Participants
n=5 Participants
63 Participants
n=7 Participants
119 Participants
n=5 Participants
Insurance Status
Medicaid
10 Participants
n=5 Participants
10 Participants
n=7 Participants
20 Participants
n=5 Participants
Insurance Status
Uninsured
3 Participants
n=5 Participants
5 Participants
n=7 Participants
8 Participants
n=5 Participants

PRIMARY outcome

Timeframe: 3 months post randomization

Population: Analysis was based on intention to treat.

We reviewed electronic health records of participants 3 months post randomization to ascertain outcome. We looked for one or both of the following (1) note in free text MD note documenting receipt of one form of colorectal cancer (CRC) screening during study period (2)lab results from fecal occult blood test, sigmoidoscopy, or colonoscopy. Participants were categorized as completing CRC screening if there was a lab result or physician note located in chart during study period. If no note or lab result was found in chart, then the participant was categorized as not completing CRC screening.

Outcome measures

Outcome measures
Measure
Usual Care Control Group
n=314 Participants
Usual Care
Intervention Group
n=314 Participants
Received Educational Outreach
Colorectal Cancer Screening Completion.
Did not Complete Screening
304 participants
283 participants
Colorectal Cancer Screening Completion.
Completed Screening
10 participants
31 participants

SECONDARY outcome

Timeframe: 6 months post randomization

Population: Analysis was based on intention to treat.

We reviewed electronic health records of participants 6 months post randomization to ascertain outcome. We looked for one or both of the following (1) note in free text MD note documenting receipt of one form of colorectal cancer (CRC) screening during study period (2)lab results from fecal occult blood test, sigmoidoscopy, or colonoscopy. Participants were categorized as completing CRC screening if there was a lab result or physician note located in chart during study period. If no note or lab result was found in chart, then the participant was categorized as not completing CRC screening.

Outcome measures

Outcome measures
Measure
Usual Care Control Group
n=314 Participants
Usual Care
Intervention Group
n=314 Participants
Received Educational Outreach
Colorectal Cancer Screening Completion
Completed Screening
38 participants
57 participants
Colorectal Cancer Screening Completion
Did not Complete Screening
276 participants
257 participants

Adverse Events

Intervention Group

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Usual Care Control Group

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Kenzie A. Cameron, PhD, MPH

Northwestern University

Phone: 312-503-3910

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place