Fit in the Aged by Professional Training

NCT ID: NCT00783159

Last Updated: 2020-12-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

69 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-06-30

Study Completion Date

2010-05-31

Brief Summary

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This intervention study tests training methods to stabilize or improve functionality in the high risk group of prefrail elderly persons.

Detailed Description

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This study aims at the improvement of muscular function by physical exercise in prefrail elderly persons. Prefrail participants are recruited according to the frailty score of Fried. Taking into account, that vitamin D supplementation reduces falls and improves muscle strength in older people, all participants are supplemented by vitamin D. Two different training methods are tested.

After a run-in period of supplementation of vitamin D for two months, participants will be randomized into three different equally sized groups (n=25): Group A will receive power training. Group B will have progressive strength training. Group C will serve as a control group. They will receive a consultation about leading a healthy life with special attention being paid to nutrition and physical activity. The intervention period lasts for 12 weeks. The 60 minutes training sessions will be held two times a week by members of the Institute of Sport Science and Sports of the University of Erlangen-Nuremberg. Follow-up visits are scheduled three and six months after intervention period.

Conditions

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Frailty Sarcopenia

Keywords

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Muscle power Frailty Exercise Vitamin D

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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A

Training I

Group Type EXPERIMENTAL

Power Training

Intervention Type PROCEDURE

Power training, Vitamin D substitution

B

Training II

Group Type EXPERIMENTAL

Strength Training

Intervention Type PROCEDURE

Strength training, Vitamin D substitution

C

Control

Group Type ACTIVE_COMPARATOR

Control

Intervention Type OTHER

Vitamin D substitution, Lifestyle consultation

Interventions

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Power Training

Power training, Vitamin D substitution

Intervention Type PROCEDURE

Strength Training

Strength training, Vitamin D substitution

Intervention Type PROCEDURE

Control

Vitamin D substitution, Lifestyle consultation

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Prefrailty according to the frailty score of Fried

Exclusion Criteria

* Sarcoidosis
* Nephrolithiasis
* Plasmacytoma
* COPD
* Inflammatory bowel disease
* Rheumatoid arthritis
* History of cancer
* Instable heart disease
* Depression (GDS\>=6)
* Dementia (MMSE\<=24)
* BMI\>35kg/m²
* Current attendance of muscle training
* Medication: immunosuppressive drugs
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Klinikum Nürnberg

OTHER

Sponsor Role collaborator

Institute of Biomedicine of Aging

UNKNOWN

Sponsor Role collaborator

University of Erlangen-Nürnberg

OTHER

Sponsor Role collaborator

Institute of Sport Science and Sport

UNKNOWN

Sponsor Role collaborator

Robert Bosch Medical Center

OTHER

Sponsor Role collaborator

University of Erlangen-Nürnberg Medical School

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Cornel C. Sieber, Prof. Dr.

Role: PRINCIPAL_INVESTIGATOR

University of Erlangen-Nürnberg

Klaus Pfeifer, Prof. Dr.

Role: PRINCIPAL_INVESTIGATOR

University of Erlangen-Nürnberg

Locations

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Institute of Biomedicine of Aging

Nuremberg, , Germany

Site Status

Countries

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Germany

References

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Schaupp A, Bidlingmaier M, Martini S, Reincke M, Schluessel S, Schmidmaier R, Drey M. Resistance training-induced improvement in physical function is not associated to changes in endocrine somatotropic activity in prefrail older adults. Arch Gerontol Geriatr. 2022 Nov-Dec;103:104792. doi: 10.1016/j.archger.2022.104792. Epub 2022 Aug 14.

Reference Type DERIVED
PMID: 36037722 (View on PubMed)

Zech A, Drey M, Freiberger E, Hentschke C, Bauer JM, Sieber CC, Pfeifer K. Residual effects of muscle strength and muscle power training and detraining on physical function in community-dwelling prefrail older adults: a randomized controlled trial. BMC Geriatr. 2012 Nov 7;12:68. doi: 10.1186/1471-2318-12-68.

Reference Type DERIVED
PMID: 23134737 (View on PubMed)

Drey M, Zech A, Freiberger E, Bertsch T, Uter W, Sieber CC, Pfeifer K, Bauer JM. Effects of strength training versus power training on physical performance in prefrail community-dwelling older adults. Gerontology. 2012;58(3):197-204. doi: 10.1159/000332207. Epub 2011 Nov 3.

Reference Type DERIVED
PMID: 22056537 (View on PubMed)

Other Identifiers

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32.5.8051.0113.0

Identifier Type: -

Identifier Source: org_study_id