Relationship of Staphylococcal Colonization to Infection

NCT ID: NCT00766259

Last Updated: 2024-05-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Study Classification

OBSERVATIONAL

Study Start Date

2009-07-31

Study Completion Date

2012-06-30

Brief Summary

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Inpatients will be prospectively have nares screened and MRSA strains collected. All clinical MRSA strains of patients will also be prospectively collected. A sensitive strain discrimination test of spa typing will be used to determine if the strains are related. Hypotheses are

1. Strain colonization durations vary and may be very short in days to weeks.
2. Colonizing strains rarely infect 3) Both 1 and 2 may be affected by the patient's co-morbidity.

Detailed Description

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Patients of special interest:

1. Skin and soft tissue infection
2. Nursing home patients
3. Vascular patients with leg lesions
4. ICU patients
5. Hemodialysis patients
6. Outpatients without history of infections(controls) will have nares screened for MRSA and then monthly for 1 year.

All strains will be saved and spa typed. Analysis of the data will be performed to answer the questions and hypotheses and to answer is the screening effort and the isolation of patients for MRSA as is in current practice worthwhile and is there any scientific data to support this practice

Conditions

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MRSA Infection

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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1

Hemodialysis

No interventions assigned to this group

2

Intensive care

No interventions assigned to this group

3

vascular patients with open wounds

No interventions assigned to this group

4

nursing home

No interventions assigned to this group

5

skin infections

No interventions assigned to this group

6

control- ambulatory care clinic patients with no infections

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Admitted and one of the co-morbid groups
* Ambulatory care patient with no infections

Exclusion Criteria

* All others
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Veterans BioMedical Research Institute

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Other Identifiers

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Eng-MRSA

Identifier Type: -

Identifier Source: org_study_id

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