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Effect of Stress on Heroin-Related Memory Retrieval

NCT ID: NCT00759005

Last Updated: 2008-09-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Study Classification

INTERVENTIONAL

Study Start Date

2007-03-31

Study Completion Date

2008-09-30

Brief Summary

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The purpose of this study is to determine whether cortisol and propranolol are effective in the modulation of stress induced heroin-related retrieval enhancement.

Detailed Description

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Conditions

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Heroin Dependence Learning and Memory

Study Groups

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A, 4

Group Type EXPERIMENTAL

propranolol and cortisol

Intervention Type DRUG

Interventions

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propranolol and cortisol

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Participants had to have met DSM-IV criteria for heroin dependence prior to abstinence.

Exclusion Criteria

* current use of any medications; current DSM-IV diagnosis of any affective, anxiety, or psychotic disorder; current dependence on any substance besides heroin and nicotine (based on DSM-IV criteria); or risk factors for untoward side effects from propranolol and cortisol (i.e., irregular heartbeats, history of cardiogenic shock, history of severe heart failure, asthma, fungal Infections, hyperlipidemia, history of hypertension, or abnormal ECG or other laboratory findings).
Minimum Eligible Age

20 Years

Maximum Eligible Age

40 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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National Institute on Drug Dependence, China

OTHER

Sponsor Role lead

Locations

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National Institute on Drug Dependence

Beijing, Beijing Municipality, China

Site Status

Countries

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China

Other Identifiers

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NIDD

Identifier Type: -

Identifier Source: org_study_id