Effects of Calcium and Phytate on Zinc Absorption

NCT ID: NCT00754390

Last Updated: 2018-07-02

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

17 participants

Study Classification

INTERVENTIONAL

Study Start Date

2005-11-30

Study Completion Date

2006-05-31

Brief Summary

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This study is determine the effects of dietary calcium and phytate on zinc absorption.

Detailed Description

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Zinc absorption is tested from 2 days of consuming each of four diets with zinc-65 isotope, followed by retention monitoring in a whole body scintillation counter for 4 weeks. All four 4 experimental diets are tested with each subject, in randomized order, for a total of 16 weeks.

Conditions

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Dietary Zinc Absorption

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

FACTORIAL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Overall Study

Participants consumed 4 experimental diets for 4 weeks each in randomized order

Group Type EXPERIMENTAL

Moderate Calcium, Low phytate Diet

Intervention Type DIETARY_SUPPLEMENT

Participants consumed diet containing 700 milligrams calcium and 440 milligrams of phytate for 4 weeks

Moderate Calcium, High Phytate Diet

Intervention Type DIETARY_SUPPLEMENT

Participants consumed diet containing 700 milligrams calcium and 1800 milligrams of phytate for 4 weeks

High Calcium, Low Phytate Diet

Intervention Type DIETARY_SUPPLEMENT

Participants consumed diet containing 1900 milligrams calcium and 440 milligrams of phytate for 4 weeks

High Calcium, High Phytate Diet

Intervention Type DIETARY_SUPPLEMENT

Participants consumed diet containing 1900 milligrams calcium and 1800 milligrams of phytate for 4 weeks

Interventions

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Moderate Calcium, Low phytate Diet

Participants consumed diet containing 700 milligrams calcium and 440 milligrams of phytate for 4 weeks

Intervention Type DIETARY_SUPPLEMENT

Moderate Calcium, High Phytate Diet

Participants consumed diet containing 700 milligrams calcium and 1800 milligrams of phytate for 4 weeks

Intervention Type DIETARY_SUPPLEMENT

High Calcium, Low Phytate Diet

Participants consumed diet containing 1900 milligrams calcium and 440 milligrams of phytate for 4 weeks

Intervention Type DIETARY_SUPPLEMENT

High Calcium, High Phytate Diet

Participants consumed diet containing 1900 milligrams calcium and 1800 milligrams of phytate for 4 weeks

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Average weight for height

Exclusion Criteria

* Medications other than birth control pills or hormone replacement therapy,
* Pregnancy within last 6 months
Minimum Eligible Age

21 Years

Maximum Eligible Age

50 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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USDA Grand Forks Human Nutrition Research Center

FED

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Janet R Hunt

Role: PRINCIPAL_INVESTIGATOR

USDA Grand Forks Human Nutrition Research Center

Locations

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United States Department of Agriculture Grand Forks Human Nutrition Research Center

Grand Forks, North Dakota, United States

Site Status

Countries

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United States

Other Identifiers

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GFHNRC042

Identifier Type: -

Identifier Source: org_study_id

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