Developmental Effects of Infant Formula Supplemented With LCPUFA

NCT ID: NCT00753818

Last Updated: 2008-09-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Study Classification

INTERVENTIONAL

Brief Summary

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The purpose of this study is to compare the effects on visual development, growth, cognitive development, tolerance, and blood chemistry parameters in term infants fed one of four study formulas containing various levels of DHA and ARA.

Detailed Description

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Conditions

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Cognitive Development Growth

Keywords

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infant formula visual development

Study Groups

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1

Group Type EXPERIMENTAL

DHA and ARA

Intervention Type OTHER

various levels of DHA and ARA

2

Group Type EXPERIMENTAL

DHA and ARA

Intervention Type OTHER

various levels of DHA and ARA

3

Group Type EXPERIMENTAL

DHA and ARA

Intervention Type OTHER

various levels of DHA and ARA

4

Control

Group Type OTHER

Control

Intervention Type OTHER

Interventions

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DHA and ARA

various levels of DHA and ARA

Intervention Type OTHER

Control

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* healthy, term, formula fed infants from 1-5 days of age

Exclusion Criteria

* history of disease that effects normal growth and development
* breast fed, or formula intolerance
Minimum Eligible Age

1 Day

Maximum Eligible Age

5 Days

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Mead Johnson Nutrition

INDUSTRY

Sponsor Role lead

Locations

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The University of Kansas Medical Center

Kansas City, Kansas, United States

Site Status

The University of Texas Southwestern Medical Center at Dallas

Dallas, Texas, United States

Site Status

Countries

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United States

References

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Liao K, McCandliss BD, Carlson SE, Colombo J, Shaddy DJ, Kerling EH, Lepping RJ, Sittiprapaporn W, Cheatham CL, Gustafson KM. Event-related potential differences in children supplemented with long-chain polyunsaturated fatty acids during infancy. Dev Sci. 2017 Sep;20(5):10.1111/desc.12455. doi: 10.1111/desc.12455. Epub 2016 Oct 16.

Reference Type DERIVED
PMID: 27747986 (View on PubMed)

Drover JR, Felius J, Hoffman DR, Castaneda YS, Garfield S, Wheaton DH, Birch EE. A randomized trial of DHA intake during infancy: school readiness and receptive vocabulary at 2-3.5 years of age. Early Hum Dev. 2012 Nov;88(11):885-91. doi: 10.1016/j.earlhumdev.2012.07.007. Epub 2012 Jul 25.

Reference Type DERIVED
PMID: 22835597 (View on PubMed)

Birch EE, Carlson SE, Hoffman DR, Fitzgerald-Gustafson KM, Fu VL, Drover JR, Castaneda YS, Minns L, Wheaton DK, Mundy D, Marunycz J, Diersen-Schade DA. The DIAMOND (DHA Intake And Measurement Of Neural Development) Study: a double-masked, randomized controlled clinical trial of the maturation of infant visual acuity as a function of the dietary level of docosahexaenoic acid. Am J Clin Nutr. 2010 Apr;91(4):848-59. doi: 10.3945/ajcn.2009.28557. Epub 2010 Feb 3.

Reference Type DERIVED
PMID: 20130095 (View on PubMed)

Other Identifiers

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3370-2(-4)

Identifier Type: -

Identifier Source: org_study_id

NCT00222157

Identifier Type: -

Identifier Source: nct_alias