IntraVitreal Triamcinolone Acetonide: Preventing Raised Eye-pressure by Tracking Elevations After Topical Steroids
NCT ID: NCT00744666
Last Updated: 2009-08-06
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
PHASE4
70 participants
INTERVENTIONAL
2008-09-30
2010-07-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
SCREENING
NONE
Study Groups
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1
Patients receive Prednisolone 1% 1gtt qid x 4 weeks. If the intraocular pressure (IOP) after the 4 weeks is \> or equal to 21 mmHg, then IVTA will be withheld. If the IOP \< 21mmHg, then patients will receive an injection of IVTA.
Prednisolone 1% topical eye drops
Prednisolone 1% 1gtt qid to the eye requiring IVTA
2
Patients will receive an injection of IVTA (no trial of Prednisolone gtts is given).
No interventions assigned to this group
Interventions
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Prednisolone 1% topical eye drops
Prednisolone 1% 1gtt qid to the eye requiring IVTA
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Pregnancy
* Breast feeding
* hx of uveitis
* hx of neovascularization of the iris or anterior chamber angle
* hx of ocular herpes simplex keratitis
* hx of glaucoma
* Unable to provide informed consent
18 Years
ALL
No
Sponsors
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Sunnybrook Health Sciences Centre
OTHER
Hotel Dieu Hospital
OTHER
Responsible Party
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Sunnybrook Health Sciences Centre
Principal Investigators
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Kenneth Eng, MD, FRCSC
Role: PRINCIPAL_INVESTIGATOR
Sunnybrook Health Sciences Centre
Jeffery Gale, MD, FRCSC
Role: PRINCIPAL_INVESTIGATOR
Hotel Dieu Hospital
Locations
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Hotel Dieu Hospital
Kingston, Ontario, Canada
The Ottawa Hospital
Ottawa, Ontario, Canada
Sunnybrook Health Sciences Centre
Toronto, Ontario, Canada
Toronto Western Hospital
Toronto, Ontario, Canada
Countries
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Central Contacts
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Facility Contacts
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References
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Jonas JB, Kreissig I, Degenring R. Intraocular pressure after intravitreal injection of triamcinolone acetonide. Br J Ophthalmol. 2003 Jan;87(1):24-7. doi: 10.1136/bjo.87.1.24.
Other Identifiers
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07142008
Identifier Type: -
Identifier Source: org_study_id
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