Suprarenal Proximal Cuff Study for Treatment of Abdominal Aortic Aneurysm

NCT ID: NCT00739401

Last Updated: 2021-12-10

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

44 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-05-05

Study Completion Date

2009-08-31

Brief Summary

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The use of a suprarenal extension device during the index AAA procedure to accommodate the patient's anatomy and to prevent or repair leakage.

Detailed Description

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Conditions

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Abdominal Aortic Aneurysm

Keywords

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AAA Aneurysm Suprarenal Proximal Cuff Extension Endograft Endovascular repair EVAR Endoleak Type I

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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1

Test subjects requiring endovascular treatment of abdominal aortic or aorto-iliac aneurysms including a proximal cuff extension.

Group Type EXPERIMENTAL

Suprarenal Proximal Cuff Extension

Intervention Type DEVICE

Powerlink 25 and 28mm Suprarenal Proximal Extensions augmenting the 25 and 28mm Powerlink bifurcated stent graft

Interventions

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Suprarenal Proximal Cuff Extension

Powerlink 25 and 28mm Suprarenal Proximal Extensions augmenting the 25 and 28mm Powerlink bifurcated stent graft

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* 18 years old
* Informed consent understood and signed
* Will comply with post-treatment follow-up requirements up to 5 years
* Candidate for Powerlink Infrarenal Bifurcated Graft

Exclusion Criteria

* Life expectancy \< 2 years
* Participating in another clinical research study
* Pregnant or lactating women
* Patient has other medical or psychiatric problems, which in the opinion of the Investigator, precludes them from participating in the Study
* Creatinine level \> 1.7mg/dl
* Renal transplant patient
* Patient with \> 75% renal artery stenosis and not eligible for PTA/stent intervention prior to suprarenal device fixation
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Endologix

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Robert Beasley, MD

Role: PRINCIPAL_INVESTIGATOR

Icahn School of Medicine at Mount Sinai

William M. Bogey, MD

Role: PRINCIPAL_INVESTIGATOR

East Carolina University Brody School of Medicine

Robert Feldman, MD

Role: PRINCIPAL_INVESTIGATOR

Munroe Regional Medical Center

Stuart Harlin, MD

Role: PRINCIPAL_INVESTIGATOR

Sacred Heart Hospital - Pensacola Research

Jeffrey Lawson, MD

Role: PRINCIPAL_INVESTIGATOR

Duke University

William Moore, MD

Role: PRINCIPAL_INVESTIGATOR

Lexington Medical Center

Charles Thompson, MD

Role: PRINCIPAL_INVESTIGATOR

Orlando Regional Medical Center

Thomas E. Topper, MD

Role: PRINCIPAL_INVESTIGATOR

Deaconess Hospital - The Heart Group

Locations

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Mount Sinai Medical Center

Miami Beach, Florida, United States

Site Status

Munroe Regional Medical Center

Ocala, Florida, United States

Site Status

Orlando Regional Hospital

Orlando, Florida, United States

Site Status

Sacred Heart Hospital - Pensacola Research Consultants

Pensacola, Florida, United States

Site Status

Methodist Medical Center of Illinois

Peoria, Illinois, United States

Site Status

Deaconess Hospital - The Heart Group

Evansville, Indiana, United States

Site Status

Duke University Hospital

Durham, North Carolina, United States

Site Status

East Carolina University - Brody School of Medicine

Greenville, North Carolina, United States

Site Status

Countries

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United States

References

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Parmer SS, Carpenter JP; Endologix Investigators. Endovascular aneurysm repair with suprarenal vs infrarenal fixation: a study of renal effects. J Vasc Surg. 2006 Jan;43(1):19-25. doi: 10.1016/j.jvs.2005.09.025.

Reference Type BACKGROUND
PMID: 16414382 (View on PubMed)

Harlin SA, Beasley RE, Feldman RL, Thompson CS, Williams JB. Endovascular abdominal aortic aneurysm repair using an anatomical fixation technique and concomitant suprarenal orientation: results of a prospective, multicenter trial. Ann Vasc Surg. 2010 Oct;24(7):921-9. doi: 10.1016/j.avsg.2010.05.008.

Reference Type RESULT
PMID: 20831993 (View on PubMed)

Related Links

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http://www.endologix.com

Sponsor Information

Other Identifiers

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IDE G990139

Identifier Type: OTHER

Identifier Source: secondary_id

CP04-002

Identifier Type: -

Identifier Source: org_study_id