A Study On An Immunostimulant Antibody In Combination With Chemotherapy For Advanced Cancer Of The Pancreas
NCT ID: NCT00711191
Last Updated: 2013-12-24
Study Results
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View full resultsBasic Information
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COMPLETED
PHASE1
22 participants
INTERVENTIONAL
2008-06-30
2011-01-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
SINGLE_GROUP
TREATMENT
NONE
Study Groups
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single arm
monoclonal antibody
CP-870,893 intravenous administration \[IV\] on day 3 of 4-week cycles
chemotherapy
gemcitabine 1000 mg/m\^2 intravenous administration \[IV\] q week \[wk\]x3 of 4-week cycles
Interventions
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monoclonal antibody
CP-870,893 intravenous administration \[IV\] on day 3 of 4-week cycles
chemotherapy
gemcitabine 1000 mg/m\^2 intravenous administration \[IV\] q week \[wk\]x3 of 4-week cycles
Eligibility Criteria
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Inclusion Criteria
* ECOG(Eastern Cooperative Oncology Group) performance status 0-1
Exclusion Criteria
* History of cancer-associated blood clots
* History of autoimmune disease
18 Years
ALL
No
Sponsors
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University of Pennsylvania
OTHER
Hoffmann-La Roche
INDUSTRY
Responsible Party
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Principal Investigators
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Pfizer CT.gov Call Center
Role: STUDY_DIRECTOR
Pfizer
Locations
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Pfizer Investigational Site
Indianapolis, Indiana, United States
Pfizer Investigational Site
Philadelphia, Pennsylvania, United States
Countries
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References
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Beatty GL, Chiorean EG, Fishman MP, Saboury B, Teitelbaum UR, Sun W, Huhn RD, Song W, Li D, Sharp LL, Torigian DA, O'Dwyer PJ, Vonderheide RH. CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans. Science. 2011 Mar 25;331(6024):1612-6. doi: 10.1126/science.1198443.
Related Links
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Other Identifiers
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A5021005
Identifier Type: -
Identifier Source: org_study_id
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