Cardiovascular Risk in Growth Hormone Deficient Young Adult Males After Completing Growth Hormone Therapy
NCT ID: NCT00711061
Last Updated: 2009-02-10
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
24 participants
OBSERVATIONAL
2008-06-30
2009-02-28
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
GH and Cardiovascular Risk Factors
NCT01877512
Effects of Growth Hormone Administration on Cardiovascular Risk in Cured Acromegalics With Growth Hormone Deficiency
NCT00182091
Effect of Growth Hormone (GH) on Cardiac Echos in GH Deficient Patients After Acromegaly Treatment
NCT01302652
Cardiovascular Effects on Growth Hormone Therapy in Adults With Growth Hormone Deficiency
NCT01698944
Growth Hormone Treatment on Phosphocreatine Recovery in Obesity
NCT01421589
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
The objectives of this study are to compare the following measurements between growth hormone deficient young males 3-7 years post completion of growth hormone treatment and age related healthy controls:
1. Carotid artery imaging
2. Metabolic and cardiac parameters
3. Body composition measurements
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
CASE_CONTROL
PROSPECTIVE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
1
18-25 year old males, growth hormone deficient, who completed growth hormone treatment 3-5 years prior to enrollment in study
No interventions assigned to this group
2
18-25 year old males, healthy, never treated with growth hormones.
No interventions assigned to this group
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Completed growth hormone therapy approximately 3-5 years prior to study enrollment
* History of multiple pituitary hormone deficiencies or growth hormone stimulation test \<7 at initiation of growth hormone therapy
* Males, 18-25 years old
* No confirmed endocrine diagnosis including Diabetes and thyroid disorders
* BMI - z-score within 2 SD of mean
Exclusion Criteria
* Family history of early cardiovascular disease (myocardial infarction or stroke \<55years of age) in first degree family members
* Any implanted device
* Medication known to interfere with glucose or lipid metabolism or to influence blood pressure
* Chronic organ illness (eg severe asthma, hepatic or nephritic conditions)
18 Years
25 Years
MALE
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Genentech, Inc.
INDUSTRY
Children's Mercy Hospital Kansas City
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Children's Mercy Hospital
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Carol Huseman, MD
Role: PRINCIPAL_INVESTIGATOR
Children's Mercy Hospital Kansas City
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Childrens Mercy Hospitals and Clinics
Kansas City, Missouri, United States
Countries
Review the countries where the study has at least one active or historical site.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
07-07-119E
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.