Spironolactone for Paroxysmal Atrial Fibrillation

NCT ID: NCT00689598

Last Updated: 2008-06-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-03-31

Study Completion Date

2011-03-31

Brief Summary

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To determine whether or not spironolactone can prevent or delay the occurrence of atrial fibrillation.

Detailed Description

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To determine whether or not adding spironolactone can prevent or delay the occurrence of paroxysmal atrial fibrillation in patients who have received propafenone treatment.

Conditions

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Atrial Fibrillation

Keywords

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Atrial fibrillation, spironolactone

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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III

Placebo

Group Type PLACEBO_COMPARATOR

Spironolactone

Intervention Type DRUG

25 mg po qd 25 mg po bid

Experimental

Drug intervention

Group Type EXPERIMENTAL

Spironolactone

Intervention Type DRUG

25 mg po qd 25 mg po bid

Placebo

Intervention Type DRUG

Spironolactone 25 mg po qd

Interventions

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Spironolactone

25 mg po qd 25 mg po bid

Intervention Type DRUG

Placebo

Spironolactone 25 mg po qd

Intervention Type DRUG

Other Intervention Names

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Aldactone Aldactone

Eligibility Criteria

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Inclusion Criteria

1. 18 to 80 Y/O,
2. Paroxysmal AF.

Exclusion Criteria

1. GPT\>100 IU/L or tota bilirubin \>2 mg/dl;
2. Creatinine \> 2 mg/dl;
3. Serum potassium \>= 5 mM;
4. Serum sodium \<=130 mM;
5. Uric acid \> 10 mg/dl。
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Taichung Veterans General Hospital

OTHER

Sponsor Role lead

Responsible Party

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Taichung Veterans General Hospital

Principal Investigators

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Tsu-Juey Wu, M.D.

Role: PRINCIPAL_INVESTIGATOR

TCVGH

Locations

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Taichung General Hospital

Taichung, , Taiwan

Site Status RECRUITING

Countries

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Taiwan

Central Contacts

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Tsu-Juey Wu, M.D.

Role: CONTACT

Phone: 886-4-23592525

Email: [email protected]

Facility Contacts

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Tsu-Juey Wu, M.D.

Role: primary

Other Identifiers

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C07061

Identifier Type: -

Identifier Source: org_study_id