Combined Sono-electro-magnetic Therapy for Treatment of Refractory Chronic Pelvic Pain Syndrome

NCT ID: NCT00688506

Last Updated: 2012-07-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-11-30

Study Completion Date

2012-07-31

Brief Summary

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Treatment of chronic pelvic pain syndrome (CPPS) is challenging for patients and physicians once conventional therapies fail.

We hypothesize that combined sono-electro-magnetic therapy can improve refractory CPPS in men. In addition, we postulate that combined sono-electro-magnetic therapy as well as placebo therapy has a significant effect on brain activity detectable by functional MRI.

Detailed Description

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Conditions

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Chronic Pelvic Pain Syndrome

Keywords

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Chronic pelvic pain syndrome Neuromodulation Brain effects Neuroimaging

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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1

Combined sono-electro-magnetic therapy

Group Type EXPERIMENTAL

combined sono-electro-magnetic therapy (Sonodyn Medico Star)

Intervention Type DEVICE

twice a day for 10 minutes during 12 weeks

2

placebo therapy

Group Type PLACEBO_COMPARATOR

placebo therapy (Placebo Sonodyn Medico Star)

Intervention Type DEVICE

twice a day for 10 minutes during 12 weeks

Interventions

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combined sono-electro-magnetic therapy (Sonodyn Medico Star)

twice a day for 10 minutes during 12 weeks

Intervention Type DEVICE

placebo therapy (Placebo Sonodyn Medico Star)

twice a day for 10 minutes during 12 weeks

Intervention Type DEVICE

Other Intervention Names

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Sonodyn Medico Star Placebo Sonodyn Medico Star device

Eligibility Criteria

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Inclusion Criteria

* CPSS III
* symptomatic \>3 months
* NIH-CPSI total score =/\>15
* NIH-CPSI pain =/\>8

Exclusion Criteria

* post void residual \>100mL
* urinary tract infection
* urethral stricture
* prostate cancer
* age \<18 years
* claustrophobia
* pacemaker, neurostimulator, insulin / pain pump
Minimum Eligible Age

18 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Insel Gruppe AG, University Hospital Bern

OTHER

Sponsor Role lead

Responsible Party

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Department of Urology, University of Bern, 3010 Bern

Principal Investigators

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Thomas M Kessler, MD

Role: PRINCIPAL_INVESTIGATOR

Department of Urology, University of Bern, 3010 Switzerland

Locations

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Department of Urology, University of Bern

Bern, , Switzerland

Site Status

Countries

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Switzerland

References

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Kessler TM, Mordasini L, Weisstanner C, Juni P, da Costa BR, Wiest R, Thalmann GN. Sono-electro-magnetic therapy for treating chronic pelvic pain syndrome in men: a randomized, placebo-controlled, double-blind trial. PLoS One. 2014 Dec 29;9(12):e113368. doi: 10.1371/journal.pone.0113368. eCollection 2014.

Reference Type DERIVED
PMID: 25546177 (View on PubMed)

Other Identifiers

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1492

Identifier Type: -

Identifier Source: secondary_id

KEK 292/07

Identifier Type: -

Identifier Source: org_study_id