Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
PHASE4
86 participants
INTERVENTIONAL
2008-06-30
2009-12-31
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Keywords
Explore important study keywords that can help with search, categorization, and topic discovery.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
1
Diacerein 50mg bid
diacerein
Diacerein 50mg bid
2
placebo 50mg bid
placebo
placebo
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
diacerein
Diacerein 50mg bid
placebo
placebo
Other Intervention Names
Discover alternative or legacy names that may be used to describe the listed interventions across different sources.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Conforming to the classification criteria of American College of Rheumatology\*
* More than 1 tender joints
* Self reported hand pain which is more than 30 mm on the Australian/Canadian Osteoarthritis Hand Index visual analogue scales (VAS) after wash out period of 2 weeks
Exclusion Criteria
* Previous history of hypersensitivity to Diacerein
* Patients who had taken oral corticosteroid or intraarticular steroid to hand joints within 3 months of enrollment
* Patients who were injected with hyaluronic acid to hand joints within 6 months of enrollment
* Patients who underwent surgery in any joints of the hands
* AST/ALT \> 2x upper normal range
* Serum Cr \> 1.4 mg/dl
* Patients who have severe comorbidities such as severe congestive heart failure or pulmonary disease
* Patients who took oral anticoagulants.
* Patients who refuse to sign the consent form
40 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Myungmoon Pharm. Co.
UNKNOWN
Seoul National University Hospital
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Eun Bong Lee
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Eun Bong Lee, MD
Role: PRINCIPAL_INVESTIGATOR
Seoul National University Hospital
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Seoul National University Hospital
Seoul, , South Korea
Countries
Review the countries where the study has at least one active or historical site.
References
Explore related publications, articles, or registry entries linked to this study.
Shin K, Kim JW, Moon KW, Yang JA, Lee EY, Song YW, Lee EB. The efficacy of diacerein in hand osteoarthritis: a double-blind, randomized, placebo-controlled study. Clin Ther. 2013 Apr;35(4):431-9. doi: 10.1016/j.clinthera.2013.02.009. Epub 2013 Mar 6.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
H-081-043-232
Identifier Type: -
Identifier Source: org_study_id