Chondroitin Sulphate Efficay/Safety in Patients With Knee Osteoarthritis and Psoriasis

NCT ID: NCT00669123

Last Updated: 2008-04-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

126 participants

Study Classification

INTERVENTIONAL

Brief Summary

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The purpouse of this study is to determine the efficacy and safety of chondroitin sulphate conventional treatment in patients with both knee osteoarthritis and plaque psoriasis.

Detailed Description

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Conditions

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Osteoarthritis Psoriasis Joint Diseases Muskuloskeletal Diseases Skin Diseases

Keywords

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Chondroitin sulphate Knee osteoarthritis Psoriasis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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2

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DRUG

1

Chondroitin sulphate

Group Type EXPERIMENTAL

Chondroitin sulphate

Intervention Type DRUG

Chondroitin sulphate 800 mg/day

Interventions

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Chondroitin sulphate

Chondroitin sulphate 800 mg/day

Intervention Type DRUG

Placebo

Intervention Type DRUG

Other Intervention Names

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Condrosan

Eligibility Criteria

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Inclusion Criteria

* Primary knee OA according to ACR criteria;
* OA of radiological stages 1 to 3 according to Kellgren-Lawrence;
* VAS of pain ≥30;
* PASI ≥ 5.

Exclusion Criteria

* Known allergy to chondroitin sulphate;
* Other bone and articular diseases such as chondrocalcinosis, Paget's disease, rheumatoid arthritis, psoriatic arthritis, acromegaly, hemochromatosis, Wilson's disease;
* Patients with skin conditions that could interfere in the clinical trial evaluation
Minimum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Bioiberica

INDUSTRY

Sponsor Role lead

Responsible Party

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Bioiberica

Principal Investigators

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Pere Benito, MD

Role: PRINCIPAL_INVESTIGATOR

Hospital del Mar

Montserrat Pérez, MD

Role: PRINCIPAL_INVESTIGATOR

Instituto Poal de Reumatología

Ingrid Möller, MD

Role: PRINCIPAL_INVESTIGATOR

Instituto Poal de Reumatología

Locations

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Hospital del Mar

Barcelona, Barcelona, Spain

Site Status

Instituto Poal de Reumatología

Barcelona, Barcelona, Spain

Site Status

Countries

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Spain

References

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Moller I, Perez M, Monfort J, Benito P, Cuevas J, Perna C, Domenech G, Herrero M, Montell E, Verges J. Effectiveness of chondroitin sulphate in patients with concomitant knee osteoarthritis and psoriasis: a randomized, double-blind, placebo-controlled study. Osteoarthritis Cartilage. 2010 Jun;18 Suppl 1:S32-40. doi: 10.1016/j.joca.2010.01.018. Epub 2010 May 10.

Reference Type DERIVED
PMID: 20399899 (View on PubMed)

Other Identifiers

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CS/IV/PSO/ART

Identifier Type: -

Identifier Source: org_study_id