A Randomised Controlled Trial of Family Mediated Exercises (FAME) Following Stroke

NCT ID: NCT00666744

Last Updated: 2008-10-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE3

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-04-30

Study Completion Date

2009-03-31

Brief Summary

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The aim of the study is to evaluate the functional recovery in two groups of primary stroke patients presenting with moderate/severe disability over a six month period through the implementation of a randomised controlled trial. The first group or the experimental group will receive routine therapy and additional lower limb exercise therapy in the form of family assisted exercises. The second group or the control group will receive routine therapy with no additional formal input from their family members. A secondary aim of the project is to evaluate the impact of the FAME programme on the person with stroke and the individual (s) assisting in the delivery of exercises.

Detailed Description

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Participants with primary stroke eligible for inclusion to the study at 2 weeks post stroke will be randomised into either a 'control' group that will receive routine therapy or an 'experimental' group that will receive routine therapy AND additional 'family mediated exercise therapy.

Training will be provided to the nominated family member (s)/friends of participants in the 'intervention' group on a weekly basis by the research physiotherapist (R1). Family members/friends will be requested to keep an exercise diary on a daily basis to document completion of exercises. The trial will continue for eight weeks with an expectation that at least 1200 additional minutes of FAME therapy will be delivered over this time period. Each FAME session is expected to last 35-40 minutes.

Exercises will include repetitive sit to stand exercises with an emphasis on improving symmetry, weight bearing exercises during standing, bridging, straight leg raises, quadriceps strengthening exercises, active/active assisted range of movement exercises for the lower limb and walking. Outcome will be assessed by a blinded outcome assessor (R2) on entry to the study, at eight weeks (post-intervention) and again three months post-intervention (follow-up)

In addition, a semi-structured interview will be carried out with a random sample of the participants and their family member (s)/friends to gain a more qualitative insight into the impact of the programme on those involved. This interview will be completed by a person unknown to the participant. (R3)

Conditions

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Weakness Balance

Keywords

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exercise frequency duration

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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1

Exercise Intervention - additional lower limb exercises will be completed by the person with stroke with the assistance of his/her family for 35 minutes daily for a period of 8 weeks.

Group Type EXPERIMENTAL

Family Mediated Exercise Therapy

Intervention Type OTHER

35 minutes of lower limb exercises to be completed by the person with stroke on a daily basis with the assistance of their family for a period of 8 weeks.

2

Participants in this group will receive routine exercise therapy following stroke

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Family Mediated Exercise Therapy

35 minutes of lower limb exercises to be completed by the person with stroke on a daily basis with the assistance of their family for a period of 8 weeks.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* diagnosis of first unilateral stroke
* Patients who score between 3.2 and 5.2 on the Orpington Prognostic Scale
* Patients participating in a physiotherapy programme
* Patients willing to give informed written consent
* Patients with family willing to participate in their assigned physiotherapy intervention programme

Exclusion Criteria

* hemiplegia of a non-vascular origin
* discharged from hospital less than two weeks following stroke
* pre-existing neurological disorder
* any lower limb orthopaedic condition that may limit exercise capacity
* aphasia
* cognitive impairment
* not willing to give written consent
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Foundation for Medical Research

OTHER

Sponsor Role collaborator

Friends of the Royal Hospital Donnybrook

UNKNOWN

Sponsor Role collaborator

University of Dublin, Trinity College

OTHER

Sponsor Role lead

Responsible Party

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University of Dublin, Trinity College

Principal Investigators

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Emma Stokes, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Dublin, Trinity College

Tara Cusack, PhD

Role: PRINCIPAL_INVESTIGATOR

University College Dublin

Locations

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Beaumont Hospital

Dublin, , Ireland

Site Status RECRUITING

MaterMisercordiae University Hospital

Dublin, , Ireland

Site Status RECRUITING

Countries

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Ireland

Central Contacts

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Emma K Stokes, PhD

Role: CONTACT

Phone: 00 353 1 896 2127

Email: [email protected]

Rose Galvin, BSc

Role: CONTACT

Phone: 00 353 1 896 3613

Email: [email protected]

Facility Contacts

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Julie Shanahan, BSc

Role: primary

Orla Friel, BSc

Role: primary

References

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Galvin R, Cusack T, Stokes E. A randomised controlled trial evaluating family mediated exercise (FAME) therapy following stroke. BMC Neurol. 2008 Jun 20;8:22. doi: 10.1186/1471-2377-8-22.

Reference Type DERIVED
PMID: 18570643 (View on PubMed)

Other Identifiers

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Irish Heart Foundation - FAME

Identifier Type: -

Identifier Source: secondary_id

08/19

Identifier Type: -

Identifier Source: org_study_id