Yunzhi as Dietary Supplement in Breast Cancer

NCT ID: NCT00647075

Last Updated: 2010-12-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE4

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-11-30

Study Completion Date

2010-12-31

Brief Summary

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The purpose of this study is to assess the effects of a dietary supplement, the traditional Asian mushroom Yunzhi, as adjuvant in the treatment of patients with breast cancer.

Detailed Description

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Conditions

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Breast Cancer

Keywords

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Breast cancer undergoing adjuvant/neoadjuvant chemotherapy symptomatic therapy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Caregivers Investigators

Study Groups

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1

Yunzhi extract 3.5 g/day

Group Type EXPERIMENTAL

Yunzhi extract

Intervention Type DIETARY_SUPPLEMENT

3.5 g/day

2

Placebo

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DIETARY_SUPPLEMENT

Placebo (starch)

Interventions

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Yunzhi extract

3.5 g/day

Intervention Type DIETARY_SUPPLEMENT

Placebo

Placebo (starch)

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

1. Women with diagnosis of breast cancer
2. Undergoing adjuvant/neoadjuvant chemotherapy with either FEC, FAC, TAC, or EC + docetaxel combinations.
3. ≥ 18 years of age
4. Performance status: 0-2
5. Ability to provide written informed consent

Exclusion Criteria

1. Any prior history of yunzhi use
2. Use of other herbal remedies during the study duration
3. Significant cardiac, pulmonary, renal, hepatic, gastrointestinal, CNS, psychiatric disease or illicit substance use/abuse that in the opinion of the investigator would make the participant a poor candidate for study participation
4. Pregnancy (for women of childbearing potential, a negative pregnancy test, urine or serum, is required within 14 days prior to randomization)
5. Systemic use of progestins, androgens or other steroids (dexamethasone is allowed if used as antiemetic therapy)
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Hospital Clinic of Barcelona

OTHER

Sponsor Role lead

Responsible Party

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Vita Green Europe, S.A.

Principal Investigators

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Pere Gascon, MD

Role: PRINCIPAL_INVESTIGATOR

Hospital Clinic

Locations

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Hospital Clinic

Barcelona, Barcelona, Spain

Site Status RECRUITING

Hospital Parc Tauli

Sabadell, Barcelona, Spain

Site Status RECRUITING

Countries

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Spain

Central Contacts

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Pere Gascon, MD

Role: CONTACT

Phone: +342275400

Email: [email protected]

Other Identifiers

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YUNZHI-BC

Identifier Type: -

Identifier Source: org_study_id