Effect of Irvingia Gabonensis (Bush Mango)on Parameters Associated With Metabolic Syndrome

NCT ID: NCT00645775

Last Updated: 2008-03-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

102 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-11-30

Study Completion Date

2007-04-30

Brief Summary

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The study investigated the use and efficacy of the seeds of African bush mango (Irvingia gabonensis)to control body weight, blood lipids and hormones in overweight and obese people.

Detailed Description

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To assess the effects of seeds of Irvingia gabonensis on body weight, fasting blood glucose, plasma total and LDL cholesterol in 102 overweight and obese participants.

The study was a 10 week randomized, double blind, placebo controlled design. participants were randomly divided into 2 groups of 51 participants each. Group 1 was the placebo group, while Group 2 was the active group. Each group received 2 daily doses of 125 mg (before meals) of either placebo or Irvingia gabonensis.

Weight as well as fasting blood was taken at baseline and at 4, 8 and 10 weeks. No major detary changes or exercises were suggested during the study period.

Conditions

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Metabolic Syndrome Obesity Dyslipidemia

Keywords

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Weight loss Antiobesity Metabolic syndrome Leptin

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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1

Compare active to placebo

Group Type PLACEBO_COMPARATOR

IGOB131

Intervention Type DIETARY_SUPPLEMENT

Comparison of 250 mg per day of Irvingia gabonensis to placebo

Interventions

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IGOB131

Comparison of 250 mg per day of Irvingia gabonensis to placebo

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* BMI\>26

Exclusion Criteria

* Diabetics Pregnant and lactating Participating in any other weight reducing program Smokers
Minimum Eligible Age

19 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Yaounde

OTHER

Sponsor Role collaborator

Gateway Health Alliance

INDUSTRY

Sponsor Role lead

Responsible Party

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Gateway Health Alliances

Principal Investigators

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Julius E Oben, PhD

Role: STUDY_DIRECTOR

Gateway Health Alliances / University of Yaounde

Locations

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Laboratory of Nutrition & Nutritional Biochemistry

Yaoundé, Centre Region, Cameroon

Site Status

Countries

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Cameroon

References

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Ngondi JL, Etoundi BC, Nyangono CB, Mbofung CM, Oben JE. IGOB131, a novel seed extract of the West African plant Irvingia gabonensis, significantly reduces body weight and improves metabolic parameters in overweight humans in a randomized double-blind placebo controlled investigation. Lipids Health Dis. 2009 Mar 2;8:7. doi: 10.1186/1476-511X-8-7.

Reference Type DERIVED
PMID: 19254366 (View on PubMed)

Other Identifiers

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GHAIGOB131CT

Identifier Type: -

Identifier Source: org_study_id