Trial Outcomes & Findings for Mirror-Box Training in Adults With Chronic Hemiparesis Secondary to Stroke (NCT NCT00643864)

NCT ID: NCT00643864

Last Updated: 2022-04-21

Results Overview

The Fugl-Meyer Assessment of Motor Function After Stroke, a widely used scale of motor recovery after stroke. The subscale upper extremity motor function was used. This test requires progressively more complex movements and hand grasps and measure speed and coordination. Each item is graded on a 3-point ordinal scale (0=cannot perform; 1=partially performs; 2=performs fully) with a minimum score of 0 and a maximum score of 66 for the upper extremity. Higher scores indicate better outcome.

Recruitment status

TERMINATED

Study phase

NA

Target enrollment

3 participants

Primary outcome timeframe

preintervention and post intervention

Results posted on

2022-04-21

Participant Flow

Medical outpatient clinic

Participant milestones

Participant milestones
Measure
Mirror Training
Training will be performed one hour a day, five days per week, Monday through Friday, for four weeks.
Pre-test Assessment
STARTED
3
Pre-test Assessment
COMPLETED
3
Pre-test Assessment
NOT COMPLETED
0
Post-test Assessment
STARTED
3
Post-test Assessment
COMPLETED
3
Post-test Assessment
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Mirror-Box Training in Adults With Chronic Hemiparesis Secondary to Stroke

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Mirror Training
n=3 Participants
Training will be performed one hour a day, five days a week, Monday through friday, for four weeks.
Age, Categorical
<=18 years
0 Participants
n=5 Participants
Age, Categorical
Between 18 and 65 years
3 Participants
n=5 Participants
Age, Categorical
>=65 years
0 Participants
n=5 Participants
Sex: Female, Male
Female
2 Participants
n=5 Participants
Sex: Female, Male
Male
1 Participants
n=5 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=5 Participants
Race (NIH/OMB)
Asian
0 Participants
n=5 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=5 Participants
Race (NIH/OMB)
Black or African American
1 Participants
n=5 Participants
Race (NIH/OMB)
White
2 Participants
n=5 Participants
Race (NIH/OMB)
More than one race
0 Participants
n=5 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants
n=5 Participants
Region of Enrollment
United States
3 Participants
n=5 Participants

PRIMARY outcome

Timeframe: preintervention and post intervention

The Fugl-Meyer Assessment of Motor Function After Stroke, a widely used scale of motor recovery after stroke. The subscale upper extremity motor function was used. This test requires progressively more complex movements and hand grasps and measure speed and coordination. Each item is graded on a 3-point ordinal scale (0=cannot perform; 1=partially performs; 2=performs fully) with a minimum score of 0 and a maximum score of 66 for the upper extremity. Higher scores indicate better outcome.

Outcome measures

Outcome measures
Measure
Mirror Training
n=3 Participants
one group pre post design
The Fugl-Meyer Assessment of Motor Function After Stroke
Fugl-Meyer Pre
45.8 score on a scale
Standard Deviation 12.6
The Fugl-Meyer Assessment of Motor Function After Stroke
Fugl-Meyer Post
58 score on a scale
Standard Deviation 0

SECONDARY outcome

Timeframe: preintervention and post intervention

The Arm Motor Ability Test evaluates disabilities in upper extremity function in activities of daily living using a quantitative and qualitative measure. The Functional Ability Scale and the Quality of Movement Scale are rated on an ordinal scale from 0-5. The score for the Functional Ability Scale ranges from 0 to 140. The score for the Quality of Movement Scale ranges from 0 to 140. Higher scores on the Functional Ability and Quality Scale of the Arm Motor Ability Test indicate more normal movement and a better outcome.

Outcome measures

Outcome measures
Measure
Mirror Training
n=3 Participants
one group pre post design
Arm Motor Ability Test
Quality Scale Pre
90.1 units on a scale
Standard Deviation 33.5
Arm Motor Ability Test
Functional Ability Post
98.5 units on a scale
Standard Deviation 53.0
Arm Motor Ability Test
Quality Scale Post
94.5 units on a scale
Standard Deviation 54.4
Arm Motor Ability Test
Functional Ability Pre
92.8 units on a scale
Standard Deviation 34.8

SECONDARY outcome

Timeframe: pre intervention and post intervention

Population: One group pre post design

The time in seconds to complete 28 tasks is recorded. The tasks are: 1 pick up utensils, 2 cut meat, 3 fork to mouth, 4 pick up sandwich, 5 sandwich to mouth, 6 pick up spoon, 7 bean in spoon, 8 spoon to mouth, 9 grasp mug handle, 10 mug to mouth, 11pick up comb, 12 comb hair, 13 grasp jar top, 14 open jar, 15 tie lace, 16 phone to ear, 17 press phone number, 18 wipe up water, 19 throw away towel, 20 paretic arm in sleeve, 21 button two buttons, 22 arms in T-shirt, 23 shirt over head, 24 straighten shirt, 25 prop on extended arm, 26 turn on light, 27 open door, 28 close door. The total time in seconds to complete all 28 tasks is recorded - as a total summary score. There is no minimum value. There is no maximum value. Lower scores (e.g., less time to complete the 28 tasks) indicate faster performance and better outcome.

Outcome measures

Outcome measures
Measure
Mirror Training
n=3 Participants
one group pre post design
Arm Motor Ability Test - Timed
pre intervention
330.7 seconds
Standard Deviation 355.4
Arm Motor Ability Test - Timed
post intervention
249.8 seconds
Standard Deviation 257.2

Adverse Events

Mirror Training

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. Mark Hirsch, Senior Scientist

CarolinasHS

Phone: 704 355 7673

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place