Trial Outcomes & Findings for Memory and the Hippocampus in Twins (NCT NCT00638885)

NCT ID: NCT00638885

Last Updated: 2015-01-15

Results Overview

Percent retention on the Wechsler Memory Scale - Logical

Recruitment status

COMPLETED

Target enrollment

142 participants

Primary outcome timeframe

2 days

Results posted on

2015-01-15

Participant Flow

Subjects recruited through Vietnam Era Twin Registry 2001-2012.

Subjects studied at baseline with no interventions.

Participant milestones

Participant milestones
Measure
Group 1
Vietnam veterans who were twins with and without posttraumatic stress disorder underwent neuropsychological testing and MRI imaging of hippocampal volume at baseline. There were no clinical interventions.
Overall Study
STARTED
142
Overall Study
COMPLETED
142
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Memory and the Hippocampus in Twins

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Group 1
n=142 Participants
Vietnam veterans who were twins with and without posttraumatic stress disorder underwent neuropsychological testing and MRI imaging of hippocampal volume at baseline. There were no clinical interventions.
Age, Categorical
<=18 years
0 Participants
n=5 Participants
Age, Categorical
Between 18 and 65 years
142 Participants
n=5 Participants
Age, Categorical
>=65 years
0 Participants
n=5 Participants
Age, Continuous
53 years
STANDARD_DEVIATION 2 • n=5 Participants
Sex: Female, Male
Female
0 Participants
n=5 Participants
Sex: Female, Male
Male
142 Participants
n=5 Participants
Region of Enrollment
United States
142 participants
n=5 Participants

PRIMARY outcome

Timeframe: 2 days

Percent retention on the Wechsler Memory Scale - Logical

Outcome measures

Outcome measures
Measure
Vietnam Veteran Twins
n=142 Participants
Vietnam veteran twins with and without PTSD.
Neuropsychological Testing of Memory
PTSD
77 percentage of WMS retention
Standard Deviation 14
Neuropsychological Testing of Memory
non PTSD
82 percentage of WMS retention
Standard Deviation 15

Adverse Events

Vietnam Twins With and Without PTSD

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

J Douglas Bremner MD

Atlanta VAMC

Phone: 404-712-9569

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place