Trial Outcomes & Findings for Comparison of Loss of Resistance Techniques (NCT NCT00638274)

NCT ID: NCT00638274

Last Updated: 2018-11-09

Results Overview

Number of participants that had successful spinal labor analgesia in each group.

Recruitment status

COMPLETED

Study phase

PHASE2

Target enrollment

356 participants

Primary outcome timeframe

24 hours

Results posted on

2018-11-09

Participant Flow

Participant milestones

Participant milestones
Measure
1-AIR
Air 3 ml used to identify epidural space Air: 3 mls used for identifying epidural space
2-SALINE
Saline 3 ml used to identify epidural space Saline: 3 mls of saline used to identify epidural space
Overall Study
STARTED
179
177
Overall Study
COMPLETED
173
172
Overall Study
NOT COMPLETED
6
5

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Comparison of Loss of Resistance Techniques

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
1-AIR
n=173 Participants
Air 3 ml used to identify epidural space Air: 3 mls used for identifying epidural space
2-SALINE
n=172 Participants
Saline 3 ml used to identify epidural space Saline: 3 mls of saline used to identify epidural space
Total
n=345 Participants
Total of all reporting groups
Age, Categorical
<=18 years
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Age, Categorical
Between 18 and 65 years
173 Participants
n=5 Participants
172 Participants
n=7 Participants
345 Participants
n=5 Participants
Age, Categorical
>=65 years
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Sex: Female, Male
Female
173 Participants
n=5 Participants
172 Participants
n=7 Participants
345 Participants
n=5 Participants
Sex: Female, Male
Male
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Region of Enrollment
United States
173 participants
n=5 Participants
172 participants
n=7 Participants
345 participants
n=5 Participants

PRIMARY outcome

Timeframe: 24 hours

Number of participants that had successful spinal labor analgesia in each group.

Outcome measures

Outcome measures
Measure
1-AIR
n=173 Participants
Air 3 ml used to identify epidural space Air: 3 mls used for identifying epidural space
2-SALINE
n=172 Participants
Saline 3 ml used to identify epidural space Saline: 3 mls of saline used to identify epidural space
Success of Spinal Labor Analgesia From Combined Spinal Epidural
163 Participants
161 Participants

SECONDARY outcome

Timeframe: 24 hours

Number of Participants with Failed Epidural Catheters and that had to be replaced at any time measured from the time of the catheter is placed until the time of delivery.

Outcome measures

Outcome measures
Measure
1-AIR
n=173 Participants
Air 3 ml used to identify epidural space Air: 3 mls used for identifying epidural space
2-SALINE
n=172 Participants
Saline 3 ml used to identify epidural space Saline: 3 mls of saline used to identify epidural space
Number of Participants With Failed Epidural Catheters
5 Participants
9 Participants

Adverse Events

1-AIR

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

2-SALINE

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Peter H. Pan, MD

Wake Forest University School of Medicine

Phone: 336-718-82748

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place