Aortic or Mitral Valve Replacement With the Biocor and Biocor Supra

NCT ID: NCT00636987

Last Updated: 2019-02-04

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

297 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-04-30

Study Completion Date

2016-03-31

Brief Summary

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The purpose of this study is to further evaluate the long-term safety and effectiveness of the Biocor and Biocor Supra Valves.

Detailed Description

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The clinical investigation is a multi-center, prospective, non-randomized, observational, FDA-required post-approval study designed to further evaluate the safety and effectiveness of the Biocor and Biocor Supra Valves.

Conditions

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Aortic Valve Insufficiency Aortic Valve Regurgitation Aortic Valve Stenosis Aortic Valve Incompetence Mitral Valve Insufficiency Mitral Valve Regurgitation Mitral Valve Stenosis Mitral Valve Incompetence

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Implanted with Biocor or Biocor Supra Valves

Group Type OTHER

Biocor and Biocor Supra valves

Intervention Type DEVICE

Replacement for a diseased, damaged, malformed aortic or mitral heart valve

Interventions

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Biocor and Biocor Supra valves

Replacement for a diseased, damaged, malformed aortic or mitral heart valve

Intervention Type DEVICE

Other Intervention Names

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Heart Valve Replacement

Eligibility Criteria

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Inclusion Criteria

* Requires aortic or mitral valve replacement (heart surgery such as bypass is allowed at the same time)
* Legal age
* Signed informed consent prior to surgery
* Willing to complete all follow-up requirements

Exclusion Criteria

* Pregnant or nursing women
* Already have had a valve replaced other than that for the scheduled replacement
* Needs another valve replaced
* Cannot return for required follow-up visits
* Have active endocarditis
* Acute preoperative neurological event (such as a stroke)
* Renal dialysis
* History of substance abuse within one year or is a prison inmate
* Participating in another study
* Had the Biocor or Biocor Supra valve implanted but then the device was explanted
* Life expectancy less than five years
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Abbott Medical Devices

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Urban Lonn, MD, PhD

Role: STUDY_DIRECTOR

Abbott Medical Devices

Locations

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Scripps Green Hospital/Scripps Clinic

La Jolla, California, United States

Site Status

USC University Hospital, Department of Cardiothoracic Surgery

Los Angeles, California, United States

Site Status

The Heart Group, PC

Evansville, Indiana, United States

Site Status

Indiana Heart Hospital

Indianapolis, Indiana, United States

Site Status

Maine Medical Center

Portland, Maine, United States

Site Status

HealthEast St. Joseph Hospital

Saint Paul, Minnesota, United States

Site Status

St. Luke's Hospital

Kansas City, Missouri, United States

Site Status

Catholic Medical Center

Manchester, New Hampshire, United States

Site Status

Robert Wood Johnson Medical School

New Brunswick, New Jersey, United States

Site Status

Valley Hospital

Ridgewood, New Jersey, United States

Site Status

Cleveland Clinic Foundation

Cleveland, Ohio, United States

Site Status

Providence St. Vincent Medical Center

Portland, Oregon, United States

Site Status

Penn State Milton S. Hershey Medical Center

Hershey, Pennsylvania, United States

Site Status

Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania, United States

Site Status

Wellmont Holston Valley Medical Center

Kingsport, Tennessee, United States

Site Status

Saint Thomas Hospital

Nashville, Tennessee, United States

Site Status

Sentara Norfolk General Hospital/Sentara Heart Hospital

Norfolk, Virginia, United States

Site Status

Countries

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United States

Other Identifiers

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0505

Identifier Type: -

Identifier Source: org_study_id

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