Effect of Celecoxib Versus Placebo Before and After Knee Surgery on Overall Use of Analgesics After Surgery
NCT ID: NCT00633438
Last Updated: 2021-02-21
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE4
204 participants
INTERVENTIONAL
2004-01-31
2004-06-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
DOUBLE
Study Groups
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B
Placebo
Matched oral capsule administered 1 hour prior to surgery and matched oral capsule administered post surgery as needed
A
Celecoxib
400 mg oral capsule as single dose administered 1 hour prior to surgery and 200 mg oral capsule as single dose administered post surgery as needed
Interventions
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Placebo
Matched oral capsule administered 1 hour prior to surgery and matched oral capsule administered post surgery as needed
Celecoxib
400 mg oral capsule as single dose administered 1 hour prior to surgery and 200 mg oral capsule as single dose administered post surgery as needed
Eligibility Criteria
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Inclusion Criteria
* Willing to participate in study for 36 hours and come to follow-up visit 7 days post surgery
Exclusion Criteria
* Received acetaminophen or low dose narcotic (vicodin/tylox) within 8 hours of surgery
* Have received oral (4 weeks), intramuscular (2 months), intra-articular (3 months) or soft-tissue (2 months) injections of corticosteroids of the first dose of study medication or intra-artcular injections of hyaluronic acid in the index joint within 9 months of the first dose of study medication
18 Years
65 Years
ALL
No
Sponsors
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Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
INDUSTRY
Responsible Party
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Principal Investigators
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Pfizer CT.gov Call Center
Role: STUDY_DIRECTOR
Pfizer
Locations
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Pfizer Investigational Site
Phoenix, Arizona, United States
Pfizer Investigational Site
St. Petersburg, Florida, United States
Pfizer Investigational Site
Baltimore, Maryland, United States
Pfizer Investigational Site
Timonium, Maryland, United States
Pfizer Investigational Site
Springfield, Massachusetts, United States
Pfizer Investigational Site
Springfield, Massachusetts, United States
Pfizer Investigational Site
Springfield, Massachusetts, United States
Pfizer Investigational Site
Springfield, Massachusetts, United States
Pfizer Investigational Site
Springfield, Missouri, United States
Pfizer Investigational Site
Columbia, South Carolina, United States
Pfizer Investigational Site
Columbia, South Carolina, United States
Pfizer Investigational Site
Columbia, South Carolina, United States
Pfizer Investigational Site
Orangeburg, South Carolina, United States
Pfizer Investigational Site
Johnson City, Tennessee, United States
Pfizer Investigational Site
San Antonio, Texas, United States
Pfizer Investigational Site
San Antonio, Texas, United States
Pfizer Investigational Site
San Antonio, Texas, United States
Pfizer Investigational Site
San Antonio, Texas, United States
Countries
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Related Links
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To obtain contact information for a study center near you, click here.
Other Identifiers
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A3191067
Identifier Type: -
Identifier Source: org_study_id
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