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Effects of Heart Rates and Variability of Heart Rates on Image Quality of Dual-Source CT Coronary Angiography

NCT ID: NCT00632918

Last Updated: 2008-12-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

149 participants

Study Classification

OBSERVATIONAL

Study Start Date

2007-10-31

Study Completion Date

2007-12-31

Brief Summary

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The purpose of this study is to investigate the effects of heart rates (including maximum heart rate, average heart rate and minimum heart rate) and variability of heart rate on image quality of DSCT coronary angiography without control of heart rate experienced in our department.

Detailed Description

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The dual-source CT (DSCT) equipped with two X-ray tubes at 90 degree offset in the gantry can provide temporal resolution 83ms using mono-segmental reconstruction technique. The recent studies about the effect of heart rate on IQ of DSCT coronary angiography which concluded in adequate diagnostic IQ of dual-source CTCA without immediate pre-scanning heart rate control included chronic users of β-blocker focused on the influences of average heart rate, heart rate variability and coronary arterial calcifications on IQ. The effect of blooming artifact of calcification on IQ by far cannot be eliminated. Here, we investigate the effects of maximum heart rate, average heart rate, minimum heart rate and heart rate variability on the motion-related IQ of DSCT coronary angiography in patients without both pre-scanning heart rate control and chronic use of β-blocker agent, compared with that in chronic users of β-blocker agents.

Conditions

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CT Coronary Angiography

Keywords

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Image quality Dual-source CT Coronary angiography Heart rate

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Exclusion Criteria

* The patients below 18 year old, patients with status post heterotopic heart transplantation (having two hearts in a chest), patients with status post coronary by-pass surgery and patients with post indwelling of coronary arterial stents
Minimum Eligible Age

21 Years

Maximum Eligible Age

78 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Far Eastern Memorial Hospital

OTHER

Sponsor Role lead

Responsible Party

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Department of Medical Imaging in Far Eastern Memorial Hospital

Principal Investigators

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Wing-Keung Cheung, MD, CCD

Role: PRINCIPAL_INVESTIGATOR

Far Eastern Memorial Hospital

Kao-Lun Wang, MD

Role: STUDY_CHAIR

Far Eastern Memorial Hospital

Chen-I Yen, BSc

Role: STUDY_CHAIR

Far Eastern Memorial Hospital

Shu-Lin Tsen, BSc

Role: STUDY_CHAIR

Far Eastern Memorial Hospital

Locations

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Department of Medical Imaing, Far Eastern Memorial Hospital

Banqiao District, Taipei, Taiwan

Site Status

Countries

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Taiwan

References

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Leschka S, Scheffel H, Desbiolles L, Plass A, Gaemperli O, Valenta I, Husmann L, Flohr TG, Genoni M, Marincek B, Kaufmann PA, Alkadhi H. Image quality and reconstruction intervals of dual-source CT coronary angiography: recommendations for ECG-pulsing windowing. Invest Radiol. 2007 Aug;42(8):543-9. doi: 10.1097/RLI.0b013e31803b93cf.

Reference Type BACKGROUND
PMID: 17620936 (View on PubMed)

Achenbach S, Ropers D, Kuettner A, Flohr T, Ohnesorge B, Bruder H, Theessen H, Karakaya M, Daniel WG, Bautz W, Kalender WA, Anders K. Contrast-enhanced coronary artery visualization by dual-source computed tomography--initial experience. Eur J Radiol. 2006 Mar;57(3):331-5. doi: 10.1016/j.ejrad.2005.12.017. Epub 2006 Jan 19.

Reference Type BACKGROUND
PMID: 16426789 (View on PubMed)

Johnson TR, Nikolaou K, Wintersperger BJ, Leber AW, von Ziegler F, Rist C, Buhmann S, Knez A, Reiser MF, Becker CR. Dual-source CT cardiac imaging: initial experience. Eur Radiol. 2006 Jul;16(7):1409-15. doi: 10.1007/s00330-006-0298-y. Epub 2006 May 13.

Reference Type RESULT
PMID: 16770652 (View on PubMed)

Matt D, Scheffel H, Leschka S, Flohr TG, Marincek B, Kaufmann PA, Alkadhi H. Dual-source CT coronary angiography: image quality, mean heart rate, and heart rate variability. AJR Am J Roentgenol. 2007 Sep;189(3):567-73. doi: 10.2214/AJR.07.2078.

Reference Type RESULT
PMID: 17715102 (View on PubMed)

Other Identifiers

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96064

Identifier Type: -

Identifier Source: org_study_id